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Cialis® (Tadalafil)

Erectile dysfunction treatment

973 reviews
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  • Cialis Daily: Take one 2.5mg/5mg tablet daily for continuous support, ideal for spontaneous sex without planning.

  • Cialis On-Demand: Take one 10mg/20mg tablet at least 30 minutes before sex, for up to 36 hours of support.

  • Can be taken with or without food.

Cialis® (Tadalafil) Information

Cialis® is one of the most popular erectile dysfunction treatments. It offers particularly long-lasting effects in comparison to the other treatment options available and can treat erectile dysfunction for up to 36 hours.
Tadalafil is the active ingredient in Cialis® and is available in a generic, unbranded tablet. Tadalafil and Cialis® are medically equivalent but tadalafil is available at a much lower cost.
Generic medicines contain the same active ingredient and are equally effective and medically equivalent to the branded products, but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product — in other words, they offer the same quality, strength, stability and effectiveness.
Cialis® 36 Hour (10/20mg) can continue to help you get and maintain erections in the 36 hours after you take the pill.
Cialis Daily® (2.5/5mg) has continuous effects for as long as you’re taking it.
Cialis® and Cialis Daily® contain different doses of the same active ingredients.
How to take Cialis® (36 Hour):
Take 1 tablet whole with a glass of water 30 minutes to 1 hour before sex. You can take it with or without food, but keep in mind it may take longer to work if taken with a heavy meal. You only need to take it when you’re planning to be sexually active.
How to take Cialis Daily®:
Take 1 tablet whole with a glass of water at the same time each day. You can take it with or without food, as it won’t affect how it works. It’s important that you take it regularly every day to ensure you get the full benefit of the medication, so it can be helpful to incorporate it into your daily routine.
Cialis® comes in two doses, either 10 mg or 20 mg. It’s recommended that you start with the 10 mg tablet and continue if this is effective, as lower doses have less chance of side effects. If you find it’s not having the desired effect on your erection after several separate attempts, you can try increasing the dose to 20 mg. If you’re still not satisfied with the results, talk to your doctor about other medication solutions for you.
Cialis Daily® is available in two strengths of 2.5 mg and 5 mg. Usually men begin with the 5 mg dose and adjust as needed. If you find that you’re experiencing side effects or the 5 mg seems to be too strong for you, you can try decreasing the dose to 2.5 mg.
Tadalafil (and its brand-name counterpart, Cialis®) comes in two forms: daily and on-demand.
The daily dose is available as 2.5mg and 5mg, and is taken once daily to maintain a steady level of medication in your system. This means you can get an erection whenever you’re aroused, which is great for those who are regularly sexually active.
Tadalafil/Cialis® can also be taken on-demand. This requires taking a 10mg or 20mg dose an hour before you plan to have sex, after which the effects remain active for up to 36 hours. You can take your medication flexibly, when required, but you must never take more than one dose per day.
Like all medications, ED treatments can cause some side effects. The most common ones are: headaches, muscle aches, back pain, flushing, low blood pressure, abnormal vision and indigestion. Please speak with your GP or pharmacist if you experience any of these side effects for a prolonged period of time.
Cialis® has fewer side effects than other medications used to treat erectile dysfunction. In fact, many men who experience nasal congestion, stomach pain, nausea and diarrhoea with other drugs find that they can take tadalafil without side effects.
Always read the patient information leaflet that’s provided inside the box of your medication before starting treatment.
Always read the patient information leaflet that’s provided inside the box of your medication before starting treatment.

Cialis® facts

  • Time to feel the effect
    From 15 mins
  • Effect lasts for
    Up to 36 hours (on-demand) or continuously (daily)
  • Available strengths
    2.5 and 5mg (daily); 10mg and 20mg (on-demand)
  • Active ingredient
    Tadalafil
  • Generic equivalent
    Tadalafil

How it works

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    1. Answer quick questions

    No GP or pharmacy visits, just a quick online consultation.

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    2. Choose your treatment

    Select from our recommended UK-licensed medications.

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    3. Get it delivered fast

    We’ll deliver direct to you.

Express delivery

Royal Mail 1st Class£2.90

Usually delivered the next working day

Special Delivery 1pm£5.95

Guaranteed next working day by 1pm

Special Delivery 9am£13.95

Guaranteed next working day by 9am

Post Office Collection£3.95

Usually collection next working day

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Why use MedExpress?

  • Trusted by more than 1.5 million customers since 2013

  • London based licenced pharmacy

  • Fast, flexible delivery options

Backed by our experienced UK-based medical team

Dr Adam Abbs picture

Dr Adam Abbs

Medical Director | MBBS, PGCCE, fHEA

GMC: 7078829

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Dr Safia Hussain

GP Lead | MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology

Cialis® (Tadalafil) prices

Starting prices for all pack sizes.
Strengths available: 2.5mg, 5mg, 10mg and 20mg

Quantity
Price from
1 Month (28 tablets) 
£69.99£2.50 a tablet
2 Months (56 tablets) 
£139.99£2.50 a tablet
3 Months (84 tablets)Saves £9.98
£199.99£2.39 a tablet
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Authored by Dr Zoë Lees. Last reviewed 16 February 2026 by Liyya Patel.