Alli (Orlistat 60mg)

Weight Loss Pills

£29.99 Includes free private prescription
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  • 1 Month (Pack of 84 Capsules) - £29.99
  • 2 Months (Double Pack of 84 capsules) - £55.99
  • 3 Months (Triple Pack of 84 capsules) - £82.99

What is Alli?

What Is Alli?

Alli (Orlistat 60mg) is used in the treatment of obesity. Alli prevents your body from absorbing the fat from the food you eat. By reducing the amount of fat that is absorbed, Alli can help you to lose weight more easily.

Alli isn't a magic bullet which makes dieting easy; it's designed to be used with a support programme, and can reward your efforts by boosting your weight loss. So for every 2 lb you work to lose, adding Alli can help you lose 1 lb more. Alli works by blocking 25% of the fat you eat from being absorbed so makes your healthy choices even healthier.

When you follow the Alli programme, you have access to a range of support tools to help you on your weight loss journey. You'll also learn new habits to help you reach and maintain a healthier weight; from setting your personal daily fat and calorie targets based on your current weight and activity levels, to which foods to avoid and dealing with cravings.

How Alli Works?

The active ingredient (orlistat) in Alli is designed to target fat in your digestive system. It stops about a quarter of the fat in your meals from being absorbed. This fat will pass out of the body in your stools. You may experience diet-related treatment effects (see section 4). It is therefore important that you commit to a lower-fat diet to manage these effects. If you do, the action of the capsules will assist your efforts by helping you to lose more weight compared to dieting alone. For every 2 kg (4 lb) you lose from dieting alone, Alli can help you lose 1 kg (2 lb) more.

How To Take

  • Alli should be taken three times a day at mealtimes - before, during or up to one hour after each meal.
  • Alli capsules should be swallowed whole with water.
  • Alli chewable tablets should be chewed and swallowed. No water is needed with Alli chewable tablets.
  • Do not take more than three capsules or chewable tablets a day.
  • Don't take Alli if you're going to eat a meal that doesn't contain fat or if you miss a meal.
  • You should also take a multivitamin every day at bedtime to ensure adequate absorption of vitamins A, D, E and K.

Side Effects

Side Effects

The most common side effects of Alli (Orlistat 60mg) include:
oily rectal discharge
passing gas with oily discharge
urgent need to have a bowel movement
oily or fatty stools
increased number of bowel movements
being unable to control your bowel movements

Information Leaflet

Patient Information Leaflet

Always read the patient information leaflet before commencing treatment. View patient information leaflet.

Authored 02 April 2020 by Dr Clare Morrison, Reviewed 02 April 2020 by Liyya Patel, Siobhan Titre Last updated 02 April 2020

Recent Alli Reviews

4.7 / 5

Based on 472 independent customer reviews taken by Feefo (see all MedExpress Reviews).

By Jordan John Black (Exeter) on 22 September 2021


Very fast delivery and Quality item


Very fast delivery and Quality item

"Great service ."
By Sally on 06 September 2021


Fantastic value, very fast service , and easy to order . Going to introduce my friends .


Fantastic value , great service . Glad my sister introduce me . Thank you.

By Mina on 24 August 2021


I am going to buy more from your sit


Is best service

By Nicola on 11 August 2021


Very good service will be buy again if I need to


Ordered on the sunday and had the item by Tuesday excellent service. Well done

By Garry on 06 August 2021


very good just started to use the product but will know more in a months time if it helps reduce my weight will buy more


this was a very good service they kept inform all the way until I got what I ordered and it was very fast service too will use these again

Read More Alli Reviews

Alli FAQ

  1. How does Alli work?

    Alli works primarily in the digestive system and prevents some of the fat from a meal from being absorbed. Alli is a non-systemically acting medicine because it acts locally in the digestive system - there is minimal absorption into the bloodstream.

  2. How long can I take Alli for?

    Alli can be taken for as long as you are losing weight by your target amount every 3 months. If you put on weight or your BMI falls below 28 you will need to discontinue Alli.

  3. How many times a day do I take Alli?

    The dose is a maximum of 3 times a day.

  4. When should I take Alli?

    Alli should be taken just before or during a meal, or up to one hour after the meal. If the meal you are eating does not contain any fat, you should not take Alli.

  5. When should I start taking Alli?

    The best time to start taking Alli would be a few days after you begin your reduced calorie lower-fat diet. If you have already started a lower-fat reduced calorie diet, you can start immediately.

  6. Can I take two doses of Alli with a meal to help me lose weight quicker?

    No. You should never take more than the recommended dose of a medicine. Take one Alli capsule at mealtimes, three times a day. This usually means one capsule at breakfast, lunch and dinner.

  7. What pack size does Alli come in?

    Alli capsules are available in packs of 42 (2 weeks),84 (4 weeks), 168 (8 weeks), 252 (12 weeks).

  8. If I eat a high-fat meal, should I take two doses of Alli?

    No, you should never take more than the prescribed dose of a medicine. Take only one Alli capsule at mealtimes, three times a day, at breakfast, lunch and dinner. Make every effort to avoid high-fat meals taking Alli. Taking Alli with a meal containing more fat than your recommended target, may increase the chances of diet-related treatment effects.

  9. Should I take Alli if I know I'm going to eat a meal high in fat content?

    If you know you are going to be eating a high-fat meal, do not take Alli with that meal. Taking Alli with a meal containing more fat than your recommended target, may increase the chances of diet-related treatment effects. However, it's important you make every effort to avoid high-fat meals or snacks while on the Alli weight loss programme.

  10. What if I eat more than three meals a day? Should I still take Alli with each meal?

    No, take no more than 3 doses of Alli a day. Just choose three meals that contain about 15 grams (Based on a diet of 1400 calories a day) of fat and take Alli with those meals. If you are eating more than 3 meals a day, you may need to check you are not exceeding your daily calorie target.

  11. Should I skip meals whilst taking Alli?

    Clinical studies have shown that Alli works best when you eat 3 healthy, low-fat meals a day, one of which is breakfast. If you skip a meal or you are certain your meal contains no fat, you can skip a dose.

  12. If Alli only works on the fat in my food, how do I lose the fat in my body?

    As you eat fewer calories on a reduced calorie, lower-fat diet - and use Alli to prevent absorption of some of the fat you eat - your body will automatically tap into its fat stores and use them for the energy it needs. This leads to weight loss as your body burns its fat.

  13. What happens if Alli is taken with a fat-free meal?

    Nothing, because there's no fat for Alli to work on. Don't take Alli if you're going to eat a meal that doesn't contain fat.

  14. Why should I take a multivitamin when I'm taking Alli?

    You should take a multivitamin every day because Alli can lower the levels of some fat-soluble vitamins absorbed by your body. The multivitamins should contain vitamins A, D, E and K. You should take the multivitamin at bedtime, when you will not be taking Alli, to help ensure that the vitamins are absorbed.

  15. What if I forget to take Alli before a meal?

    If you forget to take Alli and more than an hour has passed since your meal, do not take it. Just wait until your next meal and take Alli then. Never take two doses of Alli at the same time.

  16. What does Alli do?

    If you commit a healthy lifestyle and follow a reduced calorie, lower-fat diet, Alli can reward your hard work with 50% more weight loss. So, for every 2 lb you lose by your own efforts, Alli can help you lose 1 lb more. They work in your digestive system to prevent some of the fat in your meals from being digested and absorbed. The unabsorbed fat passes naturally out of your body in your stools.

  17. I am on a sodium-restricted diet. Is it OK to take Alli?

    The level of sodium in Alli is very low and so you do not need to take this into account if you are on a controlled sodium diet.

  18. I don't like swallowing tablets or capsules. Can I open an Alli capsule and sprinkle the contents of the capsule on my food?

    No. You must swallow the capsule whole with water. You should not break the capsule open.

  19. How long does Alli remain in my body?

    Since the time it takes people to digest food varies, the active ingredient in Alli can actually remain in your body for up to 48 to 72 hours, mainly because the time taken for food to pass through the digestive system varies from person to person. However, it only affects the fat absorption of meals that are eaten within a short time of taking Alli. Only a very small amount of Alli is absorbed into the bloodstream.

  20. Why should I take the multivitamin at bedtime?

    If you take the multivitamin with a meal, at the same time that you take Alli, it can cause some of those vitamins to be lost. So it's best to take the multivitamin at a time when you won't be taking Alli, such as bedtime.

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Our qualified team

All our doctors and pharmacists are based in the UK and are registered with the General Medical Council and General Pharmaceutical Council.

Dr Clare Morrison

General Practitioner (Prescriber)
GMC: 3441561

Avnish Patel

GPhC: 2079950

Liyya Patel

Superintendent Pharmacist
GPhC: 2083287

Choosing Generic vs Branded Alli


Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product before they can be sold - i.e. they offer the same quality, strength, stability and effectiveness.