Mounjaro price changes explained
4.2/5
What are your options?
Stay on Mounjaro
Continue with current pricing
You can stay on your current Mounjaro treatment plan without making any changes. Our clinical team will review your order and confirm the best option for continuing your treatment safely.
Reorder MounjaroWegovy is an option
Unchanged pricing from £99.99
Wegovy is a GLP-1 treatment that helps reduce appetite and support long-term weight management. Our clinicians can help you decide which option best fits your goals and ongoing treatment plan.
Speak to us
Get support from our clinicians
If you’d like to discuss your options or have any questions, our medical team is here to help. Every consultation is reviewed carefully to ensure your treatment remains safe and effective.
Get in touchCompare cost and average weight loss
In anonymised MedExpress data, people prescribed Mounjaro lost an average of around 20% of their body weight after 12 months. Individual results vary.
Wegovy vs Mounjaro
 Wegovy® (semaglutide) |  Mounjaro® (tirzepatide) |
|---|---|
Price range £99.99–£199.99 | Price range £179.99–£309.99 |
Average weight loss (in clinical studies)* 20.7% of body weight | Average weight loss (in clinical studies)* 22.5% of body weight |
Treatment schedule Weekly injection | Treatment schedule Weekly injection |
Dose adjustments Gradual, guided by your clinician | Dose adjustments Gradual, guided by your clinician |
Suitable for oral contraception? Yes | Suitable for oral contraception? No |
Injection site reactions (in studies)** Reported in 5% of participants | Injection site reactions (in studies)** Reported in 4.4% of participants |
Heart health indication*** Approved to reduce the risk of heart disease in adults with obesity or overweight and existing heart conditions | Heart health indication*** Not currently licensed for this use |
*Effectiveness: In 72 weeks, people taking Mounjaro 15mg in a clinical study lost an average of 22.5% of their body weight when taken as directed. This means that someone who weighs 100kg may lose an average of 22.5kg in 72 weeks (1 year, 5 months).
In 72 weeks, people taking Wegovy 7.2mg in a clinical study lost an average of 20.7% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 20.7kg on average in 72 weeks (1 year, 5 months).
These are examples only and not a prediction of individual results.
**In SURMOUNT-1, the pooled average for injection site reactions from 2,539 participants was 4.4% with Mounjaro. For Wegovy, this was 5.0% in the STEP-1 clinical trial of 1,961 participants.
***Heart health: Clinical trials show Wegovy can reduce the risk of heart attack, stroke and death from heart disease by up to 20% in people with obesity or who are overweight and have existing heart disease, even if they don’t have diabetes.
About switching weight loss medications
You don’t need to start over. Our clinicians can help find you a suitable Wegovy dose based on your current Mounjaro dose and tolerance.
Mounjaro and Wegovy work differently in the body, so their doses don't translate directly. There isn't currently any published research that shows how to convert a dose from one treatment to another. Because of this, switching between them isn't about finding an "equivalent" dose. Instead, your prescriber focuses on:
- How you've responded to treatment so far
- How well you've tolerated it, particularly when it comes to side effects
- Your long-term goals and individual health profile
Everyone responds differently. If you switch from Mounjaro to Wegovy, you may need to start at a lower dose and build up again. Your MedExpress prescriber will explain your options and help you decide the best next step.
Switching FAQs
Switching medications is a normal and common occurrence — it’s something medical professionals recommend regularly for conditions like high blood pressure or high cholesterol, whether it’s to reduce side effects or lower costs.
However, you may not need to switch from Mounjaro, but instead explore a lower dose. We’ll work with you to find the solution that’s right for your needs, budget and goals.
For those who need a more cost-effective option, Wegovy offers similar weight-loss results and some additional benefits, including support for heart health. If you choose to switch, our clinicians will make sure the change is safe, smooth, and tailored to you. That way, you can keep moving towards your health goals with minimal disruption.
Both Wegovy (semaglutide 7.2mg) and Mounjaro (tirzepatide 15mg) are highly effective for long-term weight loss, but they work slightly differently and may affect people differently.
In 72 weeks, people taking Wegovy 7.2mg in a clinical study lost an average of 20.7% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 20.7kg on average in 72 weeks (1 year, 5 months).*
In 72 weeks, people taking Mounjaro 15mg in a clinical study lost an average of 22.5% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 22.5kg on average in 72 weeks (1 year, 5 months).**
These are examples only. It is not a prediction of individual results.
Both can be excellent options. The right choice comes down to your health needs, goals, lifestyle and how your body responds to treatment. Our medical team will help you find what works best for you.
*STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg). Individual results vary.
**SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.
Wegovy and Mounjaro work in similar ways, so some people experience similar side effects. The most common are digestive effects such as nausea, vomiting, diarrhoea, constipation and stomach discomfort.
Side effects are usually mild to moderate and often improve as your body adjusts to treatment.
If you tolerated Mounjaro well, you may have a similar experience on Wegovy. However, everyone responds differently depending on the dose and individual factors. Your clinician will review your health and treatment history before switching, to help you move safely and comfortably.
A note about the higher Wegovy 7.2mg doseThe highest dose of Wegovy (7.2mg) can sometimes cause a temporary side effect called dysesthesia. This can feel like tingling, pins and needles, buzzing, or a mild burning sensation on the skin. It is not nerve damage and usually improves over time, even while continuing treatment.
In clinical studies:
- Around 7 in 10 people reported digestive side effects
- Around 1 in 4 people reported dysesthesia
- Around 1 in 20 people stopped treatment due to side effects
Most side effects were mild to moderate and settled over time. Your care team will monitor your response closely and can adjust your dose if needed to help manage side effects and keep your treatment safe and comfortable.
In some cases, we may recommend a lower starting dose to maximise comfort and minimise side effects during the switch. This isn't a step backwards — it's a clinically safe way to help your body adjust while keeping progress on track.
Our aim is always steady, sustainable weight loss without compromising tolerability.
Mounjaro (tirzepatide)
- Mimics two naturally occurring hormones in the body (GIP and GLP-1)
- Uses a wider range of doses (up to 15mg)
Wegovy (semaglutide)
- Mimics one hormone (GLP-1)
- Uses a different range of doses (from 0.25mg to 2.4mg)
Another way to think about it is like driving two different cars.
Wegovy is a car with a set number of gears, and you move up through them gradually as your body adapts.
Mounjaro is a different car with more gears available, and those gears work in a different way because the engine is designed differently. You can't compare "third gear" in one car with "third gear" in another and expect the same speed or feel.
In the same way, Mounjaro and Wegovy have different dose ranges and work differently in the body. The same dose number does not mean the same strength, effect, or weight loss results.
More questions? See all FAQs
Your medical team
Dr. Bryony Henderson
Dr. Bryony Henderson is Medical Director for MedExpress UK, bringing extensive experience in clinical operations, governance and digital health. She has previously held roles dedicated to delivering safe, scalable care across well-known brands. She is a recognised clinical voice contributing to award-winning campaigns, publishing on health inequalities, and appearing across national media. Here, Bryony leads clinical governance and quality, supporting the delivery of safe, innovative and accessible healthcare.
Adedayo Titiloye
Adedayo Titiloye is Superintendent Pharmacist responsible for the safe and compliant delivery of pharmacy services across MedExpress. He brings experience across community pharmacy and regional operations, including leadership roles within one of the UK’s largest independent pharmacy groups. Here, Ade focuses on building high-performing teams, improving processes and ensuring pharmacy services deliver safe, effective care at scale.
Dr. Carla Rodrigues
Dr. Carla Rodrigues is Head of Medical Operations at MedExpress, having previously held leadership roles in primary care networks and across well-known healthcare organisations, and has led scientific society groups in the field of sexual medicine. She has also completed training with MIT, Harvard and INSEAD. At HeliosX, Carla leads medical operations in the UK, overseeing the delivery of safe care pathways and upholding high standards in prescribing and clinical governance.
Dr. Kavir Matharu
Dr. Kavir Matharu is a GP Lead at MedExpress, with 10 years’ experience across a range of healthcare settings. She is a practising GP with a background in complex healthcare consulting, having worked on high-level strategic and operational challenges within the health system. She was also selected for a leadership fellowship with the National Medical Director at NHS England. Kavir has a strong interest in healthcare leadership and system improvement, with a focus on high-quality, sustainable care.
Dr. Daryl Perera
Dr. Daryl Perera is a GP Lead at MedExpress, with experience across NHS primary care, urgent care and private practice. He has extensive experience in digital healthcare and clinical leadership, and oversees clinical governance and patient safety across our digital health services. His work spans urgent care and preventative medicine, with particular interests in men’s health, obesity management, and sport and exercise medicine. Daryl has worked across a range of NHS and private healthcare organisations and previously held a GP Director role.
Dr. Sophie Dix
Head of Medical Affairs
BSc (Hons), MSc, PhD
Dr. Sophie Dix is Head of Medical Affairs at MedExpress and a behavioural neuroscientist with over 25 years’ experience across the pharmaceutical industry, charity sector and health technology. Her work has focused on understanding how to manage and treat conditions affecting both mind and body, bringing together scientific insight with real-world care. Sophie is passionate about evidence and ensuring people have access to the right treatment at the right time.
Dr. Zoe Lees
Medical Writer
BSc (Hons), MSc, PhD
Dr. Zoe Lees is a Medical Writer at MedExpress, specialising in clear, evidence-based health communications. She completed her postgraduate research at the University of Glasgow, focusing on metabolic complications of pregnancy and the role of adipose tissue function. Zoe brings a strong scientific foundation to her work and is committed to delivering content that is both accurate and accessible, grounded in robust research.
Dr. Adam Abbs
Dr. Adam Abbs is Medical Director, International at MedExpress responsible for expanding the company into new markets. He has extensive experience in asynchronous and video consultations, technology-enabled remote examinations and home biomarker testing, with a particular interest in educating both patients and doctors. Adam is a published author and is licensed to practice medicine in the UK and across the EU, and is registered in Canada.
Liyya Patel
Liyya Patel is Deputy Chief Pharmacist at MedExpress UK, with over 10 years’ experience supporting the organisation’s growth and development. She is responsible for ensuring pharmacy services are safe, compliant and meet all regulatory standards, playing a key role in maintaining high-quality clinical care. Liyya previously worked in high-volume community pharmacy settings in Central London and is a qualified pharmacist and independent prescriber.
Dr. Olivia de Rougemont
Dr. Olivia de Rougemont is a GP Lead at MedExpress with over 12 years’ experience across the NHS and private sectors. She has extensive experience in digital and in-person care, with a particular interest in women’s health, preventative medicine, and delivering patient-centred support that feels clear and accessible. Olivia also leads and mentors GPs, and brings a global perspective shaped by her experience working across different healthcare systems.
Results that speak for themselves
Chloe J. after 2 months
Rosie G. lost 25kg after 6 months
Roisin S. lost 19.5kg after 3 months
Magdalena S. lost 22kg after 4 months
Natasha T. lost 29kg after 4 months
Premila C. lost 23kg after 4 months
These customers received compensation for sharing their experience.
“The thing I like most is the aftercare. I get really helpful emails with tips and advice. After week one I’m 6lb down, so let’s see where it takes me on my weight loss journey.”
Sonia, weight loss customer
“Products are very effective. I’ve lost weight already in just 14 days so happy. Would recommend this company highly. In fact I’ve already introduced 3 people to MedExpress.”
Shireen, weight loss customer
“I am one week into treatment and feeling good — less cravings and fuller for longer in between meals. The website is really informative and ordering a straightforward process.”
Mrs Roe, weight loss customer
“I am having a good experience. No side effects presently. I love the feeling of not feeling hungry, it’s very calming for me. I am enjoying the journey so far.”
Mr Gale, weight loss customer
“Professional, quick to respond, quick delivery and the product has made me feel the most confident I have felt in years.”
Claire, weight loss customer