In case you missed it — weight loss price changes ahead. Explore your options
Mounjaro's manufacturer will increase all UK prices on 1 September, 2025.
 Wegovy |  Mounjaro |
|---|---|
Avg. weight loss Up to 15%* | Avg. weight loss Up to 20%* |
Active ingredient Semaglutide | Active ingredient Tirzepatide |
Schedule Weekly | Schedule Weekly |
Dose flexibility Increase, decrease or maintain monthly | Dose flexibility Increase, decrease or maintain monthly |
Suitable for oral contraception? Yes | Suitable for oral contraception? No |
Injection site reactions† 0.3% of patients | Injection site reactions† 8.6% of patients |
Licensed for heart health‡ Yes | Licensed for heart health‡ No |
Proven in chronic kidney disease Yes | Proven in chronic kidney disease No |
* Effectiveness: In studies, the highest dose of Mounjaro (tirzepatide) plus healthy lifestyle changes led to an average weight loss of up to 20.9% in 36 weeks and 25.3% in 88 weeks. Wegovy (semaglutide) users lost around 15% of their weight in 68 weeks with diet and exercise changes.
† Injection site reactions: Long-term studies found these in 0.3% of Wegovy users and 8.6% of Mounjaro users.
‡ Heart health: Clinical trials show Wegovy can reduce the risk of heart attack, stroke and death from heart disease by up to 20% in people with obesity or who are overweight and have existing heart disease, even if they don’t have diabetes.
Yes, switching medications is common practice by medical professionals. Our goal is to find the safest, most effective option for your needs.
Clinical studies show people using Wegovy lose around 15% of their body weight on average over 68 weeks.
We’ll match you to a suitable Wegovy dose equivalent to your current Mounjaro dose, so your treatment continues without interruption.
Wegovy is now significantly less expensive per pen.. It’s also the first GLP-1 licensed for heart health benefits, is suitable for use with oral contraception, and tends to have fewer injection site reactions.
Find your most suitable Wegovy dose by selecting your current Mounjaro dose.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
A prescriber will always check the dose is suitable for you before dispensing your order.
MedExpress customers lose an average of 20.3% body weight in 12 months. That’s four months faster than shown in studies (20.9% in 16 months).
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Management of my appetite was the biggest challenge, so the medication [Wegovy] has really just been game-changing. I've been trying to lose weight for 14 years. As soon as I knew about this medication from my research, I ordered it the same night I found out it was available.
I had tried every diet under the sun. I finally plucked up the courage… and it has changed my life. I am happier, more confident, full of energy and able to run around after my children for longer. [It] has drastically improved my physical, emotional and mental health.
I was starting to get a pain in my knee which seems to have decreased a lot since losing the weight. I don't get any more back pain. It's made me a lot more confident within myself. I actually want to go out and do things. I want to go clothes shopping. I want to enjoy things with my kids.
I can do more. I feel more energetic. I can play more with my kids, whereas before I was restricted. It's mostly the breathlessness, the being slow, being out of breath, feeling heavy, not being able to put my clothes on properly because they were too tight. It's been a brilliant experience with MedExpress.
I used to hide away in oversized clothes, just trying to feel comfortable—but I had no confidence. Now, I'm fitting back into clothes I haven't worn in years, and I actually enjoy getting dressed in the morning. I feel happier, more confident, and like I'm finally showing up as myself.
It's making me more happy about myself. I'm feeling more confident. I'm not hiding. If my friend invites me for a coffee, I won't say no anymore. I'm dressing-up! I'm taking care of myself now. I feel more happy every day. I'm more talkative. I'm going to more family events.
Backed by our team of hundreds of in-house medical and clinical experts.
Authored by Dr Clare Morrison. Last reviewed 01 February 2025 by Liyya Patel and Siobhan Titre.
