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Emla Cream is a topical numbing cream used to ease the pain of needle procedures, such as injections, vaccinations or blood tests. Emla Cream contains two active ingredients called lidocaine and prilocaine. These belong to a group of medicines called local anaesthetics.
Emla Cream works by numbing the surface of the skin for a short time. This helps to stop pain on the skin, but you may still have the feelings of pressure and touch.
The active ingredients work by altering the way signals are conducted in neurons. Usually, the nerves on your skin will send signals to your brain when they’re touched. This is how we experience pain. When Emla Cream is applied, the process that allows these signals to be sent becomes blocked — reducing or stopping the pain from being felt.
Make sure you plan ahead as Emla cream takes 30–60 minutes to achieve its numbing effect. Exact timings may vary depending on your age and the type of procedure.
Apply the cream in a thick layer, avoiding rubbing in. Cover with an airtight, watertight dressing. When it’s time for your procedure, you or your practitioner can remove the dressing and wipe off the cream.
The cream works quite quickly. It should start to numb the affected area in around 30–60 minutes. The more you use, the more it numbs the area. Exact timings may vary depending on your age and the type of procedure.
The numbing effect of Emla Cream usually lasts at least two hours. It can be left on the skin for up to five hours. The longer it is left, the longer the numbing effect will last.
Most adults can use Emla Cream, but inform your doctor or pharmacist before using Emla Cream if:
For most people, Emla Cream is very safe and doesn’t produce side effects. For those who do experience side effects, they’re usually mild and nothing to worry about. They include:
In very rare cases, some people may have an allergic reaction to Emla Cream. Seek immediate medical attention if:
Always read the patient information leaflet before starting treatment.
View patient information leaflet.Impressively quick service. Easy site to navigate and meds delivered by reliable Royal Mail, so well pleased. Thank you!
Great service, easy to navigate the questionnaire and far quicker service than waiting for the NHS services to approve and dispense your meds. Completely legitimate products, unlike so many other bogus sites. I have placed a couple of orders, even today, a Saturday, with estimated delivery this Monday. Awesome! This company has my full 5 star approval.
Full information, quick delivery, follow up email. Professional would not purchase from anyone else.
Fantastic service and very fast delivery, very happy with this service.
Very fast delivery, I am happy with the speed that I got to order what I needed and fast delivery, really needed to start taking the product. Thank you.
Such an easy way to get medication quickly. Superb service and quick delivery. I couldn’t even get through to my Drs so although this costs a bit more it’s infinitely quicker.
Fantastic and quick response, no hassle trying to get a doctor appointment, thanks MedExpress.
I have used them many times & the procedure is very easy & the delivery very quick.
This is a brilliant service and so quick and efficient. I would have had to wait god knows how long for a GP appointment for this medication.
Checked properly by a doctor before medication was prescribed and aftercare very good. Received yesterday kept up to date with the delivery and had to sign for which I like so there’s no missing parcel. Highly recommended.
Trustworthy, professional and speedy delivery service. I have used this pharmacy a few times and I would recommend!

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Dr. Bryony Henderson joins HeliosX as Medical Director for the UK and US, bringing extensive clinical operations, governance, and digital health experience from Kry/Livi and Numan. A recognised clinical voice, she has contributed to award-winning campaigns, published on health inequalities, and appeared across major national media. At HeliosX, she leads clinical governance and quality and supports the delivery of safe, innovative, scalable care.

Adam is a doctor and advocate for increasing access to healthcare internationally. He has extensive experience in video consultations, technology-enabled examinations, remote biomarker testing, and education. He is a published author and has medical licenses in the UK, Spain and Republic of Ireland.

Consultant GP and Quality Lead
MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology
Safia is a GP with experience working in the NHS with a particular interest in diabetes and weight loss management. She is passionate about the power of digital healthcare and oversees our approach to patient safety and regulatory compliance.

Declan is a pharmacist with 15 years of experience and is passionate about digital healthcare. He has extensive experience across all pharmacy sectors in the UK and Ireland. He has led the clinical and regulatory functions of some of the biggest pharmacy organisations in the UK and is excited about the future of the industry.