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Wegovy® Injectable Pen

Effective GLP-1 weight loss treatment

45,000+ service reviews
  • Lose up to 15% of your weight
  • Weekly self-injection pen
  • Supports healthy weight loss by reducing appetite and making you feel fuller
  • No subscriptions
  • First weight loss medication approved to cut heart disease risk by up to 20%*
Dosage
£119.00for 1 pen (4 doses)
Clinician

After answering some quick health questions, we’ll recommend suitable treatments for you.

Dr Paul Davis, Senior GP and Medical Lead

*In people with overweight or obesity.

Lose up to 15% of your weight with Wegovy®

lose 50% more weight than dieting alone illustration

Wegovy® information

Wegovy® (semaglutide) is an effective injectable weight loss drug for people with a BMI over 30. It’s also available for people with a BMI over 27 who have additional weight-related health concerns, like high blood pressure, Type 2 diabetes, heart disease, and raised cholesterol.
Wegovy® mimics a natural hormone in the gut that helps to control your appetite and make you feel fuller.
Wegovy® is an injectable medication that comes in a pre-filled pen. It should be used once weekly, on the same day. The pen is simple to use, and the needles are very small, so it’s relatively pain-free and easy to get used to.
Wegovy® can be injected in the abdomen, thigh or upper arm at any time during the day, with or without food. It’s recommended that you use it around the same time each week — this will regulate the medication’s effectiveness.
You’ll receive clear instructions with your first order, and the Wegovy® website has lots of useful information too.
This helpful video has more information about how to use Wegovy.
Wegovy® is an injectable weight loss medication suitable for people with a BMI of ≥ 30, or for people with a BMI ≥ 27 in the presence of a weight-related health concern such as high blood pressure, prediabetes or high cholesterol.
Wegovy® is also suitable for people with a BMI of ≥ 27 and established heart disease, to reduce the risk of major adverse cardiovascular events such as a heart attack, stroke, or death from heart disease.
If you have type 2 diabetes and a BMI less than 27, we can’t prescribe you Wegovy® for weight loss.
Your treatment starts at a low dose and then increases every four weeks. When you first start using Wegovy®, the starting dose is 0.25 mg, once a week, for four weeks. The dose will then be increased after every four weeks until you reach the recommended dose of 2.4mg a week.
This chart shows how your dosage will increase over five months:Wegovy® dosage guideOnce you’ve been on treatment for around six months, we’ll review your weight to see how much you’ve lost in that time. For us to continue prescribing Wegovy® to you, you’ll need to have lost around 5% of your initial body weight and submit your results when we check in with you.
Wegovy® is one of the most effective weight loss treatments available. Studies have shown over 85% of people using it have lost weight. Two thirds of participants lost more than 10% of their body weight, and nearly one third of people lost more than 20%. Users, on average, lost more than 15kg.
When you order Wegovy® for the first time, we’ll supply the lowest dose pen, containing 4 doses—enough for your initial 28-day treatment. It’s important to store it in a refrigerator between 2-8°C. Each box of Wegovy® comes with 4 needles, one for each weekly dose. You’ll also receive:
  • A sharps bin
  • An instruction leaflet
  • Extra tips that can help you to lose weight
To get started, complete a consultation for an injectable weight loss pen and select the starter pack. With each new order, you’ll receive your next pen and 4 needles.
When you’ve been using Wegovy® for 3 weeks, it’s time to think about ordering your next pen from us. At this time, we’ll send you a reminder to log on and complete a weight loss consultation.
If you’re responding well to treatment, we’ll prescribe and send you another pen and 4 needles in a temperature-controlled delivery packaging. It’s important to store these in a refrigerator between 2-8°C. This pack will last you 28 days. As you use the last dose in each pen, remember to return to MedExpress to reorder supplies so you can continue treatment uninterrupted.
Once you’ve been taking Wegovy® for around 6 months, we’ll need to reassess your weight to make sure we can continue to prescribe to you.
Your health and wellbeing are our top priority, so please reach out to the MedExpress clinical team if you have any concerns while taking Wegovy.
You’ll receive a sharps bin with your first order. This is a special waste bin that’s used to store sharps material, like needles, until it can be safely disposed of.
After every use, dispose of the needle into the sharps bin. After the 4 doses, and once the needle has been removed, the pen can be disposed of in your household waste or the sharps bin. When full, your sharps bin can be collected for disposal by your local council.
Once you’ve started treatment, you’ll be able to purchase more sharps bins with new orders.
  • Wegovy should be stored under 30°C or, preferably, in a fridge (2-8°C).
  • Don’t freeze your pen, or use it if it has been frozen.
  • Keep the cap on when the pen isn’t in use to protect it from light.
We’re here to support you throughout your weight loss journey, offering tips to help you manage side effects and providing reassurance if you have any concerns.
While Wegovy has helped many people reach their health goals, it’s crucial to understand what to watch for along the way. Below, we’ve outlined the most common and rare side effects, along with guidance on when to seek help.

Very common

These side effects may occur in more than 1 in 10 people and usually go away over time. They are most common when first starting Wegovy and when increasing the dose.
  • Examples: feeling sick (nausea), vomiting, diarrhoea, constipation, stomach pain, headache, fatigue.

Common

These side effects may occur in up to 1 in 10 people.
  • Examples: dizziness, indigestion, heartburn, bloating, burping, flatulence, injection site reactions (redness, swelling), gallstones, allergic reaction (e.g., rash, itching, and eczema), low blood pressure, hair loss, changes in sense of touch, changed sense of taste, gastritis.
In patients with type 2 diabetes, rapid improvements in blood sugar control can temporarily worsen diabetic eye disease (retinopathy), a common side effect of Wegovy. If you have this condition and notice eye problems while taking Wegovy, contact your GP or call 111 for advice.

Uncommon

These side effects may occur in up to 1 in 100 people.
  • Examples: kidney stones, increased heart rate, and low blood sugar (also known as hypoglycaemia).
  • Hypoglycaemia can occur in people without type 2 diabetes, and patients should look out for symptoms such as feeling hungry, dizzy, tired, weak, confused, anxious or irritable, sweating, shaking, tingling lips, heart palpitations, or blurred vision. Contact your GP or call 111 for advice if these symptoms occur.
  • SERIOUS: pancreatitis. This is inflammation of the pancreas that can cause severe stomach pain which can radiate to your back that doesn’t go away. Most patients feel very ill with pancreatitis and may present with severe vomiting that does not settle. You should call 999 or attend A&E right away if you experience these symptoms.

Rare

These side effects may occur in up to 1 in 1000 people.
  • SERIOUS: severe allergic reaction (anaphylaxis). This can present as difficulty breathing, swelling of lips, tongue and/or throat, difficulty swallowing, rapid heartbeat. You should call 999 or attend A&E right away if you experience these symptoms.
If you have any questions about side effects or how to manage them, we’re here to support you.
Always read the patient information leaflet before commencing treatment.

Wegovy® facts

  • Treatment type
    GLP-1 injectable pen
  • Average weight loss (%)
    Up to 15% of body weight
  • Average weight loss (kg)
    Up to 15kg of body weight
  • Available strengths
    0.25mg – 2.4mg
  • Active ingredient
    Semaglutide

How it works

  1. Step 1 illustration

    1. Answer quick questions

    No GP or pharmacy visits, just a quick online consultation.

  2. Step 2 illustration

    2. Choose a treatment

    Select from our recommended UK-licensed weight loss treatments.

  3. Step 3 illustration

    3. Get it delivered direct

    Your treatment arrives in discreet packaging, direct to your door.

Find a treatment

Wegovy® FAQs

Wegovy® is a once-weekly injection that’s given in the arm, leg or abdomen. It uses a very small, fine needle for a near-painless injection just below the surface of the skin. The Wegovy® pen comes ready to use, with a button that delivers the right amount of medication for your treatment stage. Once you’ve had the injection, remove the needle and dispose of it in a sharps bin.
Each Wegovy® pen contains 4 doses and will therefore last 4 weeks. The strength of the injection is increased every 4 weeks until the maximum dose is reached.
Wegovy® is one of the most effective weight loss treatments available. When used alongside a modified diet and exercise, studies have shown over almost 85% of people achieved weight loss of 5% or more, 66% achieved weight loss of 10% or more, and almost 50% achieved weight loss of 15% or more.
We need to assess your weight once you’ve been taking Wegovy® for around 6 months. If you’ve lost 5% of your initial weight at that assessment, you are likely to be able to continue using it for up to two years with clinical guidance.
Yes, around six months into treatment we will check in with you to find out how your weight loss is going.
If you have any queries or concerns at any time, you can contact our support team.
If you experience symptoms such as persistent nausea, vomiting and diarrhoea with your current Wegovy® dose, speak to our customer care team for advice. We may recommend delaying your next dose increase for a few more weeks to see if that helps improve your tolerance. We can also give you tips to help manage any symptoms and get maximum benefit from the medication. It’s important to not increase your Wegovy® dose until your body is ready, so make sure you contact MedExpress if you have persistent side effects.
If you are concerned or alarmed by your symptoms review the patient information leaflet or seek medical attention
Yes, Wegovy® is licensed for weight loss in the UK.

Always carry your Wegovy® pen in your hand luggage. Never place it in your checked baggage, as the aircraft hold can expose it to freezing temperatures that could damage the medication. Use a travel cooler to help keep your Wegovy® pen cold, especially if you’re travelling for extended periods in warm climates.

Unopened Wegovy® pens should be stored in a refrigerator between 2°C and 8°C. If that’s not possible, the pen can be kept at room temperature (up to 30°C) for up to 28 days. It’s important not to use any pen that has been exposed to temperatures outside this range.

To pass through airport security smoothly, make sure you carry your prescription with your name on it, along with the original box your medication came in. Carry your passport as your primary ID, and consider having extra proof of address (such as a utility bill) on hand in case further verification is requested.

Airline policies on travelling with medication can vary, so it’s best to contact your specific airline ahead of time to check what’s required for carrying medication on board.

If a dose is missed, it should be administered as soon as possible, within 5 days after the missed dose. If more than 5 days have passed, the missed dose should be skipped, and the next dose should be taken on the regularly scheduled day. From there, you can continue the once weekly dosing schedule.
Yes. A major clinical trial found that Wegovy reduces the risk of heart attack, stroke and death from heart disease by up to 20% in people with overweight or obesity and pre-existing heart disease — even if they don’t have diabetes.
Wegovy can support heart health by:
  • Lowering blood pressure
  • Reducing ‘bad’ cholesterol and triglycerides
  • Improving ‘good’ cholesterol
  • Reducing inflammation, a key driver of heart disease
  • Promoting weight loss, which reduces strain on the heart
Reference: Lincoff AM et al.; SELECT Trial Investigators. Semaglutide and Cardiovascular Outcomes in Obesity Without Diabetes.N Engl J Med. 2023;389(24):2221-2232. doi:10.1056/NEJMoa2307563.
People with overweight or obesity that have pre-existing heart disease.
For example, if you are living with overweight or obesity (BMI ≥ 27), and have previously had a heart attack, a stroke or poor blood flow to the limbs, you may be eligible for treatment.
Wegovy should not be used during pregnancy.
If you are planning to become pregnant, discontinue Wegovy at least two months in advance.
If you are of childbearing age and sexually active, you should use contraception while taking Wegovy. You can use oral contraceptive pills, non-oral methods such as the implant or IUD, or barrier methods like condoms.
Wegovy does not impact the effectiveness of the oral contraceptive pill.
As Wegovy should not be used during pregnancy, women of childbearing age should use effective contraception whilst using Wegovy. This includes the oral contraceptive pill, condoms or non-barrier methods.
If you experience severe diarrhoea that lasts for over 24 hours, or vomiting within three hours of taking your oral contraceptive pill, you may need a repeat dose of your oral contraceptive pill. Contact your GP or call 111 for medical advice if this occurs.
If you experience persistent vomiting or diarrhoea, consider using a non-oral contraception method. Contact your GP to discuss your options.
If you are planning to become pregnant, it is recommended that you wait at least two months after your last dose of Wegovy to begin trying.
Wegovy should not be used while breastfeeding. While we don’t know for sure how Wegovy could affect a breastfed baby, a risk can’t be ruled out.
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Backed by our experienced UK-based medical team

Dr Catriona Maybury picture

Dr Catriona Maybury

Medical Director | MBChB, MRCP, PhD

GMC: 6130975

Declan Lismore picture

Declan Lismore

Superintendent Pharmacist | MPharm, MRPharmS, MPSI, PGDip

GPhC: 2073498

Dr Paul Davis picture

Dr Paul Davis

Senior GP and Medical Lead | BSc MB BS DCH MRCGP

Dr Safia Hussain picture

Dr Safia Hussain

GP Lead | MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology

Wegovy® prices

Treatment begins with a low starting dose, which may be gradually increased every four weeks based on your progress.

Dosage
Price
0.25mgWeeks 1–4
£119.00 
0.5mgWeeks 5–8
£134.99 
1.0mgWeeks 9–12
£139.99 
1.7mgWeeks 13–16
£179.99 
2.4mgWeeks 17+
£219.99 
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Authored by Dr Clare Morrison. Last reviewed 01 February 2025 by Liyya Patel and Siobhan Titre.

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