Dr Ashwin Sharma

Article by Dr Ashwin Sharma

Your Guide To Mounjaro Dosage

‌If you’re reading this, the chances are you know about what Mounjaro can do already. This dual purpose medication is prescribed for people who are overweight or obese A weekly self-injectable prescription, it targets both GLP-1 and GIP receptors, which helps regulate blood sugar levels, control your appetite and make you feel fuller for longer. 

If your clinical practitioner decides Mounjaro is the right treatment for you – they’ll create a tiered dosage to help your body adjust to the medication and to minimise side effects [1]. 

Mounjaro dosing guidelines

Even if you’ve already tried another injectable weight loss drug before, you’ll start Mounjaro on the lowest dosage and then increase every four weeks. The starting dose for Mounjaro is a 2.5mg injection once a week[1]. Under the guidance of experts, like the clinical team here at MedExpress, your dose is then increased after every four weeks, until you reach the maximum dose of 15 mg a week. This chart shows how your dosage will increase over five months:

Preparing for your first dose

Your four weeks’ doses of Mounjaro come in a pre-filled pen (the Mounjaro KwikPen) – which you’ll use on the same day each week. The pen is simple to use and the needles are very small, so it’s relatively pain-free and easy to do. With your first 2.5mg dose – you’ll also receive a sharps bin to dispose of your KwikPens safely. 

Once you’ve prepped the injection site with alcohol swabs and are ready, you can inject your Mounjaro pen in the abdomen, thigh or upper arm at any time during the day, with or without food. It’s not advised to inject into the same site each time – so rotate weekly [2]. You’ll receive detailed instructions with your first order, and our clinical team is also on hand to offer any extra guidance. 

Afterwards, dispose of the pen safely and keep an eye out for any side effects.

Maintaining optimal results

There are a few things to remember to help ensure you get and maintain optimal results with Mounjaro. This includes integrating the medication into a healthy lifestyle and staying on top of check-ins with your clinical team.

Weight loss medication works best when taken alongside a balanced diet and regular exercise. There are some other things you can do to optimise your results like drinking plenty of water, especially before meals, to aid in fullness and hydration. Opt for smaller, nutrient-rich meals that include lean proteins, plenty of fibre, and are low in fats and sugars. And finally, chew food thoroughly and consider a short walk post-meals to support digestion and blood sugar regulation [3].

Tracking your progress is also essential for our clinical team to both monitor your health, identify side effects and to adjust your dosage over time. These check-ins are included in the cost of your medication and are all online, so it’s important to make use of them. 

If you think Mounjaro, or any of our other available medications, could help you reach your weight loss goals, start your free consultation today and our clinical experts will find the right treatment for you. 


[1] Mounjaro dosage: Form, strengths, how to inject, and more [Internet]. www.medicalnewstoday.com. 2023 [cited 2024 Mar 13]. Available from: https://www.medicalnewstoday.com/articles/drugs-mounjaro-dosage 

[2] How to Use, Dosing & Side Effects | Mounjaro® (tirzepatide) [Internet]. mounjaro.lilly.com. [cited 2024 Mar 13]. Available from: https://mounjaro.lilly.com/how-to-use-mounjaro 

[3] What to Eat on Mounjaro: A Guide for Success [Internet]. eMed UK. 2024 [cited 2024 Mar 13]. Available from: https://www.emed.com/uk/blog/health/what-to-eat-on-mounjaro-a-guide-for-success ‌

Dr Ashwin Sharma
Dr Ashwin Sharma
Dr Ashwin Sharma is a medical doctor and writer with a particular interest in health technology, artificial intelligence and medical weight loss. He completed his training at the University of Leicester and Imperial College London, and has since been exploring the intersections of medicine, technology, and communication.
Originally published March 27 2024, updated April 16 2024