Dr Adam Abbs
Medical Director | MBBS, PGCCE, fHEA
GMC: 7078829
- Take with a meal 3 times a day
- Reduces absorption of fat from food
- Lose 50% more weight than dieting alone
Start by filling out a 2 minute consultation form. We’ll then show our recommended weight loss treatments and help you choose the best option for your lifestyle.
Start by filling out a 2 minute consultation form. We’ll then show our recommended weight loss treatments and help you choose the best option for your lifestyle.
Orlos can help you lose 50% more weight than dieting alone
- UK registered pharmacy
- UK licensed treatments
- Trusted by over 1.5 million people
Orlos information
Orlos is a medication used for weight management. It contains the active ingredient orlistat, which helps prevent the absorption of fat from the food you eat. This can help you lose weight more easily.
It’s designed to be taken alongside a support programme, boosting the weight you lose from eating a balanced diet and exercising. For every 2kg you lose, Orlos can help you lose 1kg more.
Orlos and Alli are the brand names of two medications with the
same active ingredient, Orlistat 60mg. They’re both equally
effective — the only difference is that Orlos is available at a
lower price.
If you’ve previously tried losing weight through diet and exercise without results, you may consider other treatments. Orlos is clinically proven to help you lose 50% more weight than just dieting alone.
Orlos is only suitable for people with a BMI over 28.
Start a 2 minute consultation now to see if you’re eligible for treatment.
Orlos contains the active ingredient orlistat, which attaches itself to some of the enzymes in your body that break down fat. This stops you from absorbing some of the fat from the food you eat.
The medication blocks around a quarter of the fat from the food you eat from being digested. Any fat that isn’t digested is passed from your body in your stools.
Orlos should be taken three times a day at mealtimes — before, during or up to one hour after each meal. Capsules should be swallowed whole with water.
Do not take more than three Orlos capsules per day. You can skip a dose if you’re eating a meal that doesn’t contain fat, or if you miss a meal.
Orlos can interfere with the absorption of vitamins into your body, so you should take a multivitamin supplement daily at night to ensure you’re getting enough of vitamins A, D, E and K.
Orlos is designed to be used alongside a support programme. For
every 2kg your efforts help you lose, Orlos can help you lose
1kg more. It works by blocking 25% of the fat you eat from being
absorbed, so it makes your healthy choices even healthier.
Orlos can cause side effects, including wind with or without oily spotting, sudden or more frequent bowel motions and soft stools. Not everybody experiences them, but if you do, they usually settle after a few weeks once you get used to the medication. For more information, see the Patient Information Leaflet.
There are typically two kinds of prescription weight management medications. Some are appetite suppressants. Others, like Orlos, reduce the absorption of fat by your body.
If you’ve tried Orlos without the desired results, you should speak to your GP about other treatment options.
Always read the patient information leaflet before starting treatment.View patient information leaflet
85,000+ verified customer reviews
“Super fast discreet packaging”
Didn’t know I could get the meds online in first place. The process of actually getting was so simple few questions and check up...
“Very handy”
Absolutely essential resource for vital medication in these post-covid times. Many people still unable to see their GPs, have...
“Have reordered refills”
Quick and easy process for ordering with a simple questionnaire to find the correct medication for you. Arrives promptly.
“5*”
Helping me to lose weight along with a healthy low fat diet.
“Very quick delivery”
Very easy to follow and order products as required, and very quick delivery.
“Responsible sellers”
I’ve been using for a short time, it works really well & sold responsibly. I would recommend this company to everyone... I’ve used...
“Extremely reliable”
An extremely reliable service provider, been using them for years.
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Fantastic and quick online service 😊
“Competitively priced”
Excellent service, quick delivery, competitively priced.
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Good website, easy to use and found what I wanted and ordered with ease.
“It was easy to order”
It was easy to order the medication after answering a few medical questions. I am happy that they ask you all these medical...
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Such an easy way to get medication quickly. Superb service and quick delivery. I couldn’t even get through to my Drs so although...
“Great service”
Reasonably priced products, fast postage, easy to understand website.
“I recommend”
A good selection of medicines, quality products, fast delivery.
“Fast postage”
Reasonably priced products, fast postage, easy to understand website.
Orlos facts
- Medicine typeLipase inhibitor
- Results compared to dieting aloneFor every 2kg you lose, Orlos can help you lose 1kg more.
- Available strengths60mg
- Active ingredientOrlistat
- Branded equivalent
How it works
1. Answer quick questions
No GP or pharmacy visits, just a quick online consultation.
1. Answer quick questions
No GP or pharmacy visits, just a quick online consultation. Share your symptoms and a brief medical history in around two minutes, all from the comfort of your home.
2. Choose your treatment
Select from our recommended UK-licensed medications.
2. Choose your treatment
Select from our recommended UK-licensed medications. You don’t need an existing prescription.
3. Get it delivered fast
We’ll deliver direct to you.
3. Get it delivered fast
We’ll deliver direct to you. We always use discreet logo-free packaging, so only you know what’s inside. After it arrives, get ongoing support from our team.
Express delivery
Royal Mail 1st Class£2.90
Usually delivered the next working day
Special Delivery 1pm£5.95
Guaranteed next working day by 1pm
Special Delivery 9am£13.95
Guaranteed next working day by 9am
Post Office Collection£3.95
Usually collection next working day
Why use MedExpress?
Trusted by more than 1.5 million customers since 2013
London based licenced pharmacy
Fast, flexible delivery options
Backed by our experienced UK-based medical team
Dr Safia Hussain
GP Lead | MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology
Orlos prices
Starting prices for all pack sizes.
Quantity
Price
4 weeks (84 capsules)
£18.99£0.23 a capsule
8 weeks (168 capsules)Saves £0.99
£36.99£0.23 a capsule
12 weeks (252 capsules)Saves £1.98
£54.99£0.22 a capsule
Authored by Dr Zoë Lees. Last reviewed 16 February 2026 by Liyya Patel.