Choosing the correct strength


Tadalafil 2.5mg (Daily)
Recommended starting dose for patients who have found Cialis 5mg too strong.

Tadalafil 5mg (Daily)
Recommended starting dose for patients for patients who want to take daily treatment. Take one pill daily and the effects will be continuous.

Tadalafil 10mg (36 Hour)
Recommended starting dose for patients who haven't tried Cialis (Tadalafil) before. Each pill is taken 30 minutes before sex and the effects last up to 36 hours.

Tadalafil 20mg (36 Hour)
Recommended if you have previously taken Cialis (Tadalafil) 10mg 4 or more times without any side effects any found they did not have the desired effect. Each pill is taken 30 minutes before sex and the effects last up to 36 hours.

Choosing Generic vs Branded Tadalafil


Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product before they can be sold - i.e. they offer the same quality, strength, stability and effectiveness.

Tadalafil (Generic Cialis)

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Quantity Tadalafil 2.5mg Tadalafil 5mg
1 Month (28 tablets) £29.99 £34.99
2 Months (56 tablets) £59.99 £69.99
3 Months (84 tablets) £79.99 £104.99
Quantity Tadalafil 10mg Tadalafil 20mg
4 tablets £19.99 £19.99
8 tablets £29.99 £29.99
12 tablets £39.99
16 tablets £49.99 £49.99
24 tablets £69.99 £69.99
28 tablets £79.99
32 tablets £89.99 £89.99
64 tablets £139.99 £139.99

Tadalafil Info

What is Tadalafil?

Tadalafil is the generic version of the Cialis, one of the most popular erectile dysfunction treatments.

Tadalafil is the name of the active ingredient in Cialis and is a medication used to treat erectile dysfunction. It offers particularly long lasting effects in comparison to the other treatment options available and can produce results for up to 36 hours after taking a single pill in helping you to get and keep an erection.

What is the difference between Cialis and Tadalafil?

Tadalafil is the active ingredient in Cialis and is available in a generic, unbranded tablet. Tadalafil and Cialis are medically equivalent but Tadalafil is available at a much lower cost.

Generic medicines contain the same active ingredient and are equally effective and medically equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product - i.e. they offer the same quality, strength, stability and effectiveness.

Visit our Generic Medicine FAQ for more information.

(read more about Cialis vs Tadalafil)

What is Tadalafil Daily?

Tadalafil daily capitalises on the long duration of action of tadalafil to provide a regular solution to erectile dysfunction. It comes in lower doses but should be taken every day. This means that you don’t need to time the medication before you will be sexually active but simply take a pill every day and you will always be ready for action.

How does Tadalafil work?

The active ingredient in Tadalafil is a type of drug called a PDE-5 (phosphodiesterase type 5) inhibitor. The majority of drugs used to treat erectile dysfunction work in the same way and increase the blood flow needed to the penis that is needed for an erection to occur.

Usually an enzyme in the body makes the muscles around the blood vessels in the penis stay tight and keeps the blood vessel thin. Tadalafil stops this enzyme from working properly, which allows the blood vessels to expand and more blood can pass through, resulting in an erection.

Tadalafil is effective for many men, independent of what the cause of the condition is, because it works on the very last step of the process needed for an erection to occur. On the other hand, as it works only on a physical level, it won’t help to increase sexual desire. 

How to take Tadalafil?

Tadalafil 36-Hour and Tadalafil Daily both contain the same medication but have different purposes and are there for taken differently.

How to take Tadalafil 36 Hour:

Take 1 tablet whole with a glass of water 30 minutes to 1 hour before planning to be sexually active. You can take it with or without food, but keep in mind it may take longer to work if taken with a heavy meal. You only need to take Tadalafil when you are going to be sexually active.

How to take Tadalafil Daily:

Take 1 tablet whole with a glass of water at the same time each day. You may take it with or without food, as it will not affect how well it works. It is important that you take it regularly every day to ensure you get the full benefit of the medication, so it can be helpful to incorporate it into your daily routine (e.g. with coffee at breakfast).

What dose should you take? 

Tadalafil 36-Hour comes in two doses, either 10 mg or 20 mg. It is recommended to begin with the 10 mg tablet and continue if this is effective, as lower doses have less chance of side effects. If you find it is not having the desired effect on your erection after several separate attempts, you can try increasing the dose to 20 mg. If you are still not satisfied with the results, talk to your doctor about other medication solutions for you.

Tadalafil Daily is available in two strengths of 2.5 mg and 5 mg. Usually men begin with the 5 mg dose and adjust as needed. If you find that you are experiencing side effects or the 5 mg seems to be too strong for you, you can try decreasing the dose to 2.5 mg.

How long does it take to work?

Tadalafil has a benefit over other erectile dysfunction medications because it is so quick to work, often effective enough to allow sexual intercourse just 20 minutes after taking the pill. This is because it is absorbed into the body more easily and goes into action sooner. While you can take Tadalafil with or without food, it may take slightly longer to work if you take it with or soon after a large meal.

For Tadalafil Daily, it can take up to 5 days for the full effect to come into effect, as the low dose builds up gradually. However, after this time it will work continuously. 

How long does Tadalafil last?

Tadalafil has an extremely long duration of action in comparison to other erectile dysfunction medications and has been noted to work up to 36 hours after taking the pill.

Tadalafil Daily goes one step further to provide you with a ceaseless solution to erectile dysfunction. As it is a daily medication, you will always be ready for sexual activity.

Side Effects

Tadalafil Side Effects

Like all medications, Tadalafil has side effects that affect some men that take this medication. Some common side effects of Tadalafil are: 

  • Headaches
  • Face Flushing
  • Dyspepsia

Notably, Tadalafil has fewer side effects than other medications used to treat erectile dysfunction. In fact, many men who experience nasal congestion, stomach pain, nausea and diarrhoea with other drugs find that Tadalafil doesn’t give them these symptoms.


Alternatives to Tadalafil


For many men suffering from erectile dysfunction the primary cause may be related to psychological issues and not physical ones.

In these cases, counselling can prove to be a very effective form of treatment. Talking with a mental health professional will help to address issues of stress, anxiety or depression, which can all contribute to erectile dysfunction. For further information contact your GP.

Other ED Medications

We offer a range of ED medications. View our full range erectile dysfunction treatments.

Information Leaflet

Patient Information Leaflet

Always read the patient information leaflet before commencing treatment. View patient information leaflet.

Authored 22 April 2014 by Dr Clare Morrison, Reviewed 02 April 2020 by Liyya Patel, Siobhan Titre Last updated 02 April 2020

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