UK-licensed treatments, designed to fit into your lifestyle and support healthy eating.
†Studies show that pairing the highest dose of certain weight loss treatments with healthy lifestyle changes leads to an average weight loss of up to 20.9% in 36 weeks and up to 25.3% in 88 weeks. Read more
*Studies show semaglutide users lost 15% of their weight in 68 weeks, when combined with diet and exercise changes. A major clinical trial found that Wegovy reduces the risk of heart attack, stroke and death from heart disease by up to 20% in people in people living with obesity or who are overweight and have pre-existing heart disease — even if they don’t have diabetes.
Everything you need to feel informed and confident on your GLP-1 journey.
Visit GuideMedExpress customers lose an average of 20.3% body weight in 12 months. That's four months faster than shown in studies (20.9% in 16 months).
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105kg
No GP or pharmacy visits, just a quick online consultation.
Our medical team will review your answers and approve.
Your treatment arrives in discreet packaging, delivered to your door.
“Mounjaro has changed my life. I am finally eating to fuel my body. Emotional binge eating is no longer a part of my life. MedExpress has been a fantastic company to deal with and I can’t recommend them enough. Thank you for helping me get my life back!”
Kirsten D.
Lost 3st 10lbs (23kg) with MedExpress
Clinically proven weight loss treatments target your metabolic patterns, helping you lose weight and keep it off.
Targets the reward centre in your brain, so you’ll feel more satisfied after each meal and less likely to experience food focused thoughts.
Slows down the rate at which your stomach empties, helping to reduce your overall appetite.
Keeps your blood sugar level stable after eating, preventing spikes that can lead to increased hunger and cravings.
Eli Lilly, the manufacturer of Mounjaro, has increased the price of all dose strengths in the UK to align with prices across mainland Europe. This change means that in the UK, Wegovy is now a more cost-effective GLP-1 treatment option for weight management.
We know changes like this can feel unexpected and can lead to frustration. But our priority is to help you continue your weight loss journey with minimal disruption and find the treatment that best supports your health goals and fits your lifestyle.
Find out more
Yes. With the recent price increase for Mounjaro, Wegovy has become the more cost-effective option for weight loss and obesity management with prices starting from £99.99 a month.
Switching medications is a normal and common occurrence — it’s something medical professionals do regularly for conditions like high blood pressure or high cholesterol, whether it’s to reduce side effects or lower costs. We’ll work with you to find the treatment that’s right for your needs, budget and goals.
Read our guide to switching
Mounjaro currently shows greater average weight loss in clinical trials, and as of July 2025, it remains the most effective medication available for weight management.
That said, Wegovy is still highly effective and delivers meaningful, lasting results. At the current maximum dose (2.4 mg), studies show people lose around 15% of their body weight on average over 68 weeks — with 10.3% loss at 6 months. This is far more than many achieve through lifestyle changes or older medications alone.
Later this year, a higher-strength Wegovy (7.2 mg) will become available. In clinical trials, people taking this dose lost an average of 21% of their body weight, with about one-third losing 25% or more. Side effects were similar to those seen at the 2.4 mg dose.
Wegovy also offers other benefits, including support for heart health, no impact on oral contraceptive effectiveness, and a lower cost than Mounjaro.
Wegovy and Mounjaro work in similar ways, so they can cause similar side effects. If you’ve been tolerating Mounjaro well, you’re less likely to experience new or increased side effects when switching to an equivalent Wegovy dose.
The most common side effects include nausea, vomiting, diarrhoea, constipation, and stomach pain. Wegovy may also cause fatigue or headaches in some people. These symptoms are often mild and temporary, and can sometimes be linked to dehydration or not eating enough nutrient-rich foods.
Our clinical team will create a personalised transition plan to help you move to Wegovy with equivalent efficacy and minimal risk of side effects.
If you have questions or want tips on managing side effects, visit our Weight Loss Health Guide
Wegovy is now significantly less expensive per pen. It’s also the first GLP-1 licensed for heart health benefits, is suitable for use with oral contraception, and tends to have fewer injection site reactions.
Learn more about how treatments compare
Studies show that pairing the highest dose of certain weight loss treatments with healthy lifestyle changes leads to an average weight loss of up to 20.9% in 36 weeks and up to 25.3% in 88 weeks.
Simply start a free online consultation, answering some quick questions to check your eligibility.
You'll then see recommended treatments for you to choose from.
After checkout you'll be prompted to upload some quick photos to confirm your identity.
Your order will then be delivered quickly and discreetly, directly to your home.
Weight loss treatments are suitable for people with a BMI over 30. For individuals with weight related health concerns, they may be eligible with a BMI over 27. These related concerns include high blood pressure, diabetes, heart disease and raised cholesterol.
If you have Type 2 diabetes and a BMI less than 27, we can’t prescribe these treatments for weight loss.
No, at MedExpress you can reorder your treatment as you need it. There's no ongoing contract or hidden fees, and you're always in control.
