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Start by filling out a 2 minute consultation form. We'll then show our recommended weight loss treatments and help you choose the best option for your lifestyle.
Trusted by over
weight loss customers
Trusted by over
weight loss customers
UK registered pharmacy
UK licensed treatments
Trusted by over 1.5 million people
If you've previously tried losing weight through diet and exercise without results, you may consider other treatments. Xenical (Orlistat 120mg) is clinically proven to help you lose 50% more weight than just dieting alone.
Xenical (Orlistat 120mg) is only suitable for people with a BMI over 30, or people with a BMI over 28 who have conditions related to weight, such as diabetes or high blood pressure.
Start a 2 minute consultation now to see if you're eligible for treatment.
Xenical (Orlistat 120mg) attaches itself to some of the enzymes in your body that break down fat. This stops you from absorbing the fat from the food you eat.
The medication blocks around one third of the fat from the food you eat from being digested. Any fat that isn't digested is passed from your body in your stools. Xenical (Orlistat 120mg) only blocks fat absorption, and causes weight loss, when taken alongside meals that contain fat. Taking it alongside low-fat foods has no impact.
Xenical (Orlistat 120mg) isn't a stimulant or an appetite suppressant. It only works within your digestive system, so it shouldn't affect your heart rate, brain or ability to sleep.
When you start taking Xenical (Orlistat 120mg), you'll be given a target to lose 5% of your current weight in the first 3 months. If you do this, you can continue with treatment. Pharmacists can prescribe orlistat for up to two years.
Each time you order Xenical (Orlistat 120mg), you'll need to update the pharmacist with your current weight. If your weight goes up across any 3 month period, you'll stop treatment. If you lose enough weight to drop out BMI below 28, we can no longer supply orlistat.
Some people find they don't lose weight with orlistat. You can take a 6 month break and try another course of treatment, or speak to your GP about your options.
Take one 120mg capsule with a drink at each main meal that contains fat, up to a maximum of three per day. Each time you take it, your meal should contain no more than 30% of calories from fat. This can help you lose weight and reduce the potential gastrointestinal side effects from the medication.
You should evenly divide your daily intake of fat, carbohydrates and protein across three main meals. Take orlistat during meals or up to an hour afterwards. If you occasionally miss a meal, or eat a meal without fat, you can skip your dose. Taking more than three 120mg capsules a day hasn't been shown to have any extra weight loss benefit.
Xenical (Orlistat 120mg) interferes with your body's absorption of fat-soluble vitamins. You should take a daily multivitamin supplement that contains beta carotene and vitamins A, D, E and K once a day, at least two hours before or after taking orlistat.
Like all medicines, orlistat can cause side effects, including wind with or without oily spotting, sudden or more frequent bowel motions and soft stools. Not everybody experiences them, and they usually settle after a few weeks. For more information, see the Patient Information Leaflet.
There are typically two kinds of prescription weight management medications. Some are appetite suppressants. Others, like Xenical (Orlistat 120mg), reduce the absorption of fat by your body.
If you've tried orlistat without the desired results, you should speak to your GP about other treatment options.
Always read the patient information leaflet before starting treatment. View patient information leaflet
Impressively quick service. Easy site to navigate and meds delivered by reliable Royal Mail, so well pleased. Thank you!
Great service, easy to navigate the questionnaire and far quicker service than waiting for the NHS services to approve and dispense your meds. Completely legitimate products, unlike so many other bogus sites. I have placed a couple of orders, even today, a Saturday, with estimated delivery this Monday. Awesome! This company has my full 5 star approval.
Full information, quick delivery, follow up email. Professional would not purchase from anyone else.
Fantastic service and very fast delivery, very happy with this service.
Very fast delivery, I am happy with the speed that I got to order what I needed and fast delivery, really needed to start taking the product. Thank you.
Such an easy way to get medication quickly. Superb service and quick delivery. I couldn't even get through to my Drs so although this costs a bit more it's infinitely quicker.
Fantastic and quick response, no hassle trying to get a doctor appointment, thanks MedExpress.
I have used them many times & the procedure is very easy & the delivery very quick.
This is a brilliant service and so quick and efficient. I would have had to wait god knows how long for a GP appointment for this medication.
Checked properly by a doctor before medication was prescribed and aftercare very good. Received yesterday kept up to date with the delivery and had to sign for which I like so there's no missing parcel. Highly recommended.
Trustworthy, professional and speedy delivery service. I have used this pharmacy a few times and I would recommend!
Lipase inhibitor
Up to 50% more weight loss
120mg (prescription strength)
Orlistat

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Dr. Bryony Henderson joins HeliosX as Medical Director for the UK and US, bringing extensive clinical operations, governance, and digital health experience from Kry/Livi and Numan. A recognised clinical voice, she has contributed to award-winning campaigns, published on health inequalities, and appeared across major national media. At HeliosX, she leads clinical governance and quality and supports the delivery of safe, innovative, scalable care.

Adam is a doctor and advocate for increasing access to healthcare internationally. He has extensive experience in video consultations, technology-enabled examinations, remote biomarker testing, and education. He is a published author and has medical licenses in the UK, Spain and Republic of Ireland.

Consultant GP and Quality Lead
MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology
Safia is a GP with experience working in the NHS with a particular interest in diabetes and weight loss management. She is passionate about the power of digital healthcare and oversees our approach to patient safety and regulatory compliance.
Available in a range of pack sizes. Start a 2 minute consultation to see the best treatment option and price for you.
| Pack size | Price per capsule | Price |
|---|---|---|
| 2 weeks (42 capsules) | £1.24 a capsule | £51.99 |
| 4 weeks (84 capsules) | £0.83 a capsule | £68.99 |
| 8 weeks (168 capsules) | £0.72 a capsule | £119.99 |
| 12 weeks (252 capsules) | £0.64 a capsule | £159.99 |