Welcome to your GLP-1 guide

You’ll usually increase your dose every four weeks until you reach your maintenance dose. This dose is the amount that provides the best results while keeping side effects manageable. For some people, this will be the maximum recommended dose. For others, it may be lower, if that’s where you feel best and see steady progress.

When starting Wegovy, you’ll begin with 0.25mg once a week for the first four weeks. Your dose then increases every four weeks until you reach the recommended maintenance dose of 2.4mg per week.

Reminder: The right dose for you is one where you’re seeing steady weight loss (around 0.5–1 kg per week) and feel able to maintain it.

If things feel too fast (or side effects become difficult to manage), you can stay on a lower dose for longer.

Our clinical team will check in on your progress. To continue prescribing Wegovy, you’ll need to have lost at least 5% of your initial body weight after six months. If not, our team will work with you to explore further options.

When starting Mounjaro, you’ll begin with 2.5 mg once a week for the first four weeks. Your dose then increases every four weeks until you reach the recommended maintenance dose of 15 mg per week.

Reminder: The right dose for you is one where you’re seeing steady weight loss (around 0.5–1 kg per week) and feel able to maintain it.

If things feel too fast (or side effects become difficult to manage), you can stay on a lower dose for longer.

Our clinical team will check in on your progress. To continue prescribing Mounjaro, you’ll need to have lost at least 5% of your initial body weight after six months.

Do I have to increase my dose?

No. If you’re happy with your current dose and your results, you can stay there.

What happens if I miss a dose?

Mounjaro: Take the missed dose as soon as possible within four days. If more than four days have passed, skip it and take your next dose as scheduled.

Wegovy: Take the missed dose as soon as possible within five days. If more than five days have passed, skip it and take your next dose as scheduled.

If you’re unsure, contact our clinical team for advice.

Can I skip to a higher dose?

No. Dose increases must follow the recommended schedule for safety and to minimise side effects. If you’ve been using Wegovy or Mounjaro with another provider, we’ll need evidence of your prescription before prescribing a higher dose.

How long does a pen last?

• Each pen contains four doses and lasts four weeks. Dose strength increases every four weeks until you reach your maximum or maintenance dose.

What if I can’t tolerate my new dose?

If you experience symptoms like persistent nausea, vomiting, or diarrhoea, speak to our clinical team. We may advise staying on your current dose longer, or stepping down to reduce side effects.

Restarting medication after a gap

Less than 8 weeks
You can either stay on your previous dose (if it worked well) or move up to the next dose if you tolerated it well and want to support further weight loss.

Between 8 and 12 weeks
Your prescriber will decide whether to continue your previous dose or step down to a lower one, based on your response.
Maximum restarting dose: Wegovy 1 mg, Mounjaro 10 mg

Between 12 weeks and 6 months
Your prescriber may recommend continuing your previous dose, stepping down, or restarting from the beginning.
Maximum restarting dose: Wegovy 1mg, Mounjaro 5mg

More than 6 months
You’ll need to restart at the lowest dose.

Switching between Wegovy and Mounjaro

If you haven’t yet reached a weight loss plateau, we recommend continuing your current treatment for consistency. If you do wish to switch, your prescriber will help you choose the right dose.

• If you’re not experiencing side effects, we recommend switching to the equivalent dose in the dosing table.
• If you are experiencing side effects, consider starting on a lower dose when switching.

Dosing table