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Rizatriptan - Migraine Treatment information
Rizatriptan works by stimulating receptors called serotonin (or 5-HT) receptors that are found in the brain, which causes the blood vessels in the brain to contract. The narrowing of the blood vessels reverses the widening, which is thought to be one of the causes of migraines.
A migraine is a common condition, which affects millions of people across the UK. A migraine is characterized by a severe throbbing headache. Pain is usually felt at the front or side of the head. Approximately 20% of women and 7% of men experience migraines.
Like any medicines, Rizatriptan can cause side effects, but not everybody may experience them. Some symptoms may be caused by the migraine itself.
Common side effects of Rizatriptan include pain, heaviness, pressure or tightness in the chest, throat or other parts of the body, or unusual sensations, including numbness, tingling and warmth or cold. These effects may be intense but generally pass quickly. Some people also experience nausea, dry mouth and drowsiness. These side effects are usually mild and improve on their own.
Painkillers: Over the counter painkillers such as paracetamol, aspirin or Nurofen may help to reduce the symptoms of migraines. They are most effective when taken as soon as the migraine starts.
Triptans: Triptans are medications that can help to reverse the changes in the brain that may cause migraines. We offer a wide range of triptan migraine medication.
Always read the patient information leaflet before commencing treatment.
View patient information leaflet.Rizatriptan is a popular migraine treatment, which belongs to a class of medications known as triptans. Triptans are not the same as painkillers, instead they work by reversing the changes in the brain which can cause migraines. By reversing these changes, Rizatriptan works to treat the cause of the migraine as well as reducing the symptoms.
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Dr. Bryony Henderson
Dr. Bryony Henderson is Medical Director for MedExpress UK, bringing extensive experience in clinical operations, governance and digital health. She has previously held roles dedicated to delivering safe, scalable care across well-known brands. She is a recognised clinical voice contributing to award-winning campaigns, publishing on health inequalities, and appearing across national media. Here, Bryony leads clinical governance and quality, supporting the delivery of safe, innovative and accessible healthcare.
Adedayo Titiloye
Adedayo Titiloye is Superintendent Pharmacist responsible for the safe and compliant delivery of pharmacy services across MedExpress. He brings experience across community pharmacy and regional operations, including leadership roles within one of the UK’s largest independent pharmacy groups. Here, Ade focuses on building high-performing teams, improving processes and ensuring pharmacy services deliver safe, effective care at scale.
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Dr. Carla Rodrigues is Head of Medical Operations at MedExpress, having previously held leadership roles in primary care networks and across well-known healthcare organisations, and has led scientific society groups in the field of sexual medicine. She has also completed training with MIT, Harvard and INSEAD. At HeliosX, Carla leads medical operations in the UK, overseeing the delivery of safe care pathways and upholding high standards in prescribing and clinical governance.
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Dr. Kavir Matharu is a GP Lead at MedExpress, with 10 years’ experience across a range of healthcare settings. She is a practising GP with a background in complex healthcare consulting, having worked on high-level strategic and operational challenges within the health system. She was also selected for a leadership fellowship with the National Medical Director at NHS England. Kavir has a strong interest in healthcare leadership and system improvement, with a focus on high-quality, sustainable care.
Dr. Daryl Perera
Dr. Daryl Perera is a GP Lead at MedExpress, with experience across NHS primary care, urgent care and private practice. He has extensive experience in digital healthcare and clinical leadership, and oversees clinical governance and patient safety across our digital health services. His work spans urgent care and preventative medicine, with particular interests in men’s health, obesity management, and sport and exercise medicine. Daryl has worked across a range of NHS and private healthcare organisations and previously held a GP Director role.
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BSc (Hons), MSc, PhD
Dr. Sophie Dix is Head of Medical Affairs at MedExpress and a behavioural neuroscientist with over 25 years’ experience across the pharmaceutical industry, charity sector and health technology. Her work has focused on understanding how to manage and treat conditions affecting both mind and body, bringing together scientific insight with real-world care. Sophie is passionate about evidence and ensuring people have access to the right treatment at the right time.
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Dr. Zoe Lees is a Medical Writer at MedExpress, specialising in clear, evidence-based health communications. She completed her postgraduate research at the University of Glasgow, focusing on metabolic complications of pregnancy and the role of adipose tissue function. Zoe brings a strong scientific foundation to her work and is committed to delivering content that is both accurate and accessible, grounded in robust research.
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Liyya Patel
Liyya Patel is Deputy Chief Pharmacist at MedExpress UK, with over 10 years’ experience supporting the organisation’s growth and development. She is responsible for ensuring pharmacy services are safe, compliant and meet all regulatory standards, playing a key role in maintaining high-quality clinical care. Liyya previously worked in high-volume community pharmacy settings in Central London and is a qualified pharmacist and independent prescriber.
Dr. Olivia de Rougemont
Dr. Olivia de Rougemont is a GP Lead at MedExpress with over 12 years’ experience across the NHS and private sectors. She has extensive experience in digital and in-person care, with a particular interest in women’s health, preventative medicine, and delivering patient-centred support that feels clear and accessible. Olivia also leads and mentors GPs, and brings a global perspective shaped by her experience working across different healthcare systems.