Choosing Generic vs Branded Treclin


Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product before they can be sold - i.e. they offer the same quality, strength, stability and effectiveness.

Treclin (Tretinoin) Gel

Acne Treatment

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Our Prices

Quantity Treclin (Tretinoin) Gel
1 x 30g £39.99
2 x 30g £74.99
3 x 30g £109.99

Treclin Information

What is Treclin?

Treclin contains tretinoin and an antibiotic known as Clindamycin. It limits the growth of bacteria associated with acne and the inflammation caused by these bacteria. Tretinoin normalizes the growth of superficial skin cells and causes normal shedding of the cells that clog the hair follicles in areas with acne. This prevents the build-up of sebum and the formation of early acne lesions (blackheads and whiteheads).

Treclin Gel is used to treat acne (spots) in young people who are going through or have gone through puberty, and in adults. Treclin helps to:

  • loosen blackheads and whiteheads so that they come out more easily
  • stop new blackheads, whiteheads and spots from forming
  • lower the number of red, swollen acne spots.

What is Tretinoin?

Tretinoin is a vitamin A derivative that belongs to a class of medicines known as retinoids. Tretinoin was patented in 1957 and approved for medical use in 1962. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. Tretinoin is an effective treatment for acne and has also been licensed for the treatment of fine wrinkles from sun-aged skin. It works to treat acne by helping the skin so that blocked pores are less likely. This helps to prevent spots.

What is the difference between Treclin and Retin-A?

Retin-A is a brand name version of a tretinoin gel manufactured by Janssen. This product is no longer available in Europe. Treclin contains the same active ingredient Tretinoin as well as the antibiotic Clindamycin.

How to Use Treclin Gel

  1. Wash your hands.
  2. Completely remove any make-up.
  3. Wash the area with a mild soap and warm water, and dry gently.
  4. Put a thin layer of gel on the affected skin, using your fingertips, and smooth in.
  5. Apply to all of the area of your skin which has acne, not just each spot.
  6. Wash your hands after using the gel.

Side Effects

Side Effects

These effects can occur on the area of skin where you use the gel. If they cause you a problem, try using Isotrex less often, or stop using it for a few days until the irritation goes away, then start again. Stop using Isotrex if the irritation does not go away:
  • redness or peeling of your skin, especially during the first few weeks of use
  • slight stinging or skin pain
  • skin irritation or tenderness
  • skin burning sensation
  • dry skin
  • itching

Information Leaflet

Patient Information Leaflet

Always read the patient information leaflet before commencing treatment. View patient information leaflet.

Authored 22 April 2014 by Dr Clare Morrison Reviewed 31 January 2019 by Liyya Patel, Siobhan Titre Last updated 11 November 2018

Recent Treclin Reviews

4.6 / 5

Based on 18 independent customer reviews taken by Feefo (see all MedExpress Reviews).

"Good service"
By Reem on 16 August 2018


Acne medication - working so far


Really prompt service and exactly what I was looking for. I will definitely be using you in the future!

"Safe, secure and fast. 5 stars from me"
By Florence (Halifax) on 22 June 2018


This product makes my skin look lovely. I use it everyday and a tube lasts about 8 - 10 weeks.


Very easy to use and a quick delivery.

"Genuine. Quick efficient"
By Janet on 02 May 2018


Works as expected. Good results


Very quick efficient service. No problems at all. Genuine product. I have no hesitation in recommending. Have used them 3 times

By Julie on 26 April 2018


Medexpress had exactly what I was looking for and it arrived super quick


I have bought from medexpress a few times now and have received excellent service each time. I will continue to use them and wouldn’t hesitate to recommend them!

"Great service"
By Aimee on 19 April 2018


Great treatment! My skin has really cleared up! Use with spf30 at least though


Very quick delivery! Loving the cream it’s really helping my skin

Read More Treclin Reviews

Discreet Service

Plain packaging

Option to collect from
your local Post Office™

local branches

How our service works

It’s quick, easy, and safe to order from MedExpress — your fully regulated, London based online pharmacy.

Free online

Start a free 2 minutes online consultation with simple questions about your health.


Our UK medical team will then recommend a treatment and issue a free prescription.


Your treatment will be sent direct from our London pharmacy in discreet packaging.

Watch our video to find out more

Our qualified team

All our doctors and pharmacists are based in the UK and are registered with the General Medical Council and General Pharmaceutical Council.

Dr Clare Morrison

General Practitioner (Prescriber)
GMC: 3441561

Dr Heather Currie

General Practitioner (Prescriber)
GMC: 2613354

Dr Syed Arfeen

Primary Care Physician
GMC: 6031426

Delivery Information

We’ve got a range of delivery options that suit you. All medication is sent using non-branded, discreet packaging.

Delivery service Price Details
Signed For 1st Class £2.90

Usually Next Working Day (including Saturdays). May take up to 3 working days.

Orders placed before 4pm on weekdays will be dispatched the same day.

Special Delivery 1pm Guaranteed £5.95

Guaranteed Delivery Before 1pm Next Working Day (including Saturdays to residential addresses).

Orders placed before 4pm on weekdays will be dispatched the same day.

Special Delivery 9am Guaranteed £13.95

Guaranteed Delivery Before 9am Next Working Day (including Saturdays to residential addresses).

Orders placed before 4pm on weekdays will be dispatched the same day.

Post Office Collection £3.95

Collect from your local Post Office.

Usually Next Working Day (including Saturdays). May take up to 3 working days.

Same Day Courier (London Only) £4.95-£19.95 (depends on distance)

Same day delivery (available Monday - Friday on orders placed before 4pm). Signature required on delivery.

Orders over the weekend will be delivered on Monday.

Delivery to remote Scottish Highlands & British Isles may not be guaranteed and may take longer than 1 day (more info) .

This product is not available for international shipping

Find out more about our delivery services