Differin (Adapalene) 0.1%

Prescription Acne Treatment

Differin Cream
For sensitive or dry skin
Differin Gel
For normal or oily skin
Want it delivered by Saturday, 31 October?

Our Prices

Differin Cream

  • 1 Tube - £33.00
  • 2 Tubes - £62.00
  • 3 Tubes - £85.00

Differin Gel

  • 1 x 45g - £33.00
  • 2 x 45g - £62.00
  • 3 x 45g - £85.00

What is Differin?

What is Differin?

Differin is a gel that is used in the treatment of moderate to severe acne. It contains the active ingredients adapalene.

Adapalene belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.

How do I apply Differin?

Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.

Do not apply to broken skin.

How do I buy Differin?

Differin is a prescription only medicine and cannot be bought over the counter. If you are interested in this medicine, why not fill out our consultation questionnaire? This will be reviewed by one of our expert prescribers who will advise if this medicine is suitable and safe for you.

How long does it take to see results?

As with all medicines applied to the skin in the treatment of acne, you may not see results for up to eight weeks. It is important to be consistent in your application of this gel in order for it to work properly.

Is there anybody who cannot use Differin?

Differin is not suitable for those with a hypersensitivity to any of the ingredients. Do not use in pregnancy. Avoid sunlight and UV lamps while using this medicine. Do not use other acne products containing retinoids or benzoyl peroxide while using this medicine or products that are irritating, drying or exfoliating to the skin.

Side Effects

Side Effects

Some people can experience stinging sensation, dryness, scaling and burning sensitivity when they first use this medicine. This presents worst during the first week of use and then tends to settle.

Information Leaflet

Patient Information Leaflet

Always read the patient information leaflet before commencing treatment. View patient information leaflet.

Authored 02 April 2020 by Dr Clare Morrison, Reviewed 02 April 2020 by Liyya Patel, Siobhan Titre Last updated 02 April 2020

Recent Differin Reviews

4.9 / 5
5
16
4
2
3
0
2
0
1
0

Based on 18 independent customer reviews taken by Feefo (see all MedExpress Reviews).

"Great service and very good price. Would definitely recommend."
By Juliana on 08 September 2020

Product:

Great product. Definitely works on my spots. I could see improvement in few days after applying it just once per day.

Service:

Easy to navigate website. Reasonably priced products and fast delivery. Excellent service overall. Would definitely recommend to a friend.

"Great service, great products"
By Hannah (Hook) on 05 June 2020

Product:

My purchase arrived quickly and was excellent quality. Will definitely purchase from MedExpress in the future

Service:

Very fast delivery, easy to use website. Excellent product. Will definitely use service in the future.

"Would definitely use again"
By Judith (Birmingham) on 23 June 2019

Product:

Does exactly what it’s supposed to do

Service:

Very pleased with service

"reliable service"
By Doug on 21 March 2019

Product:

arrived as desrcibed good product

Service:

good service

"Excellent company and service"
By Fiona on 15 August 2018

Product:

Good product. It really does work

Service:

I would highly recommend this company. They website it clear, well set out and easy to use. The service was fantastic. I would definitely use them again

Read More Differin Reviews

Discreet Service

Plain packaging
guaranteed

Option to collect from
your local Post Office™

10,500+
local branches

How our service works

It’s quick, easy, and safe to order from MedExpress — your fully regulated, London, United Kingdom based online pharmacy.

Free online
consultation

Start a free 2 minutes online consultation with simple questions about your health.

Order
medication

Our UK medical team will then recommend a treatment and issue a free prescription.

Express
delivery

Your treatment will be sent direct from our London pharmacy in discreet packaging.

Watch our video to find out more

Our qualified team

All our doctors and pharmacists are based in the UK and are registered with the General Medical Council and General Pharmaceutical Council.

Dr Clare Morrison

General Practitioner (Prescriber)
GMC: 3441561

Dr Heather Currie

General Practitioner (Prescriber)
GMC: 2613354

Dr Syed Arfeen

Primary Care Physician
GMC: 6031426

Choosing Generic vs Branded Differin

X

Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product before they can be sold - i.e. they offer the same quality, strength, stability and effectiveness.