Choosing Generic Vs Branded Naproxen tablets


Generic medicines contain the same active ingredient and are equally effective and medically equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product - i.e. they offer the same quality, strength, stability and effectiveness.

Generic medicines are required meet the same standards of safety, quality and efficacy as the branded medication. To receive market approval from the European Medicines Agency and MHRA, a generic medicine must be 'bioequivalent' to the originator product.

Naproxen 250/500mg Tablets

Daily tablet for arthritis pain relief

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What is Naproxen?

Naproxen is a painkiller that belongs to a group of medications called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). It’s used for the relief of pain and inflammation in joints and muscles. 

How does Naproxen work?

Prostaglandin is the chemical in our body which is responsible for causing pain and inflammation. Naproxen works by reducing the levels of prostaglandin in the body, which reduces pain and inflammation.

Taking Naproxen

How should I take Naproxen?

Naproxen comes in two different strengths, 250mg and 500mg.

250mg or 500mg can be taken up to twice a day. A gap of at least 6-8 hours must be kept between doses. Naproxen tablets should be swallowed whole with a glass of water and should be taken with or after food to minimise potential side effects.

When can I expect to see results?

Naproxen can work as quickly as 1 hour after taking the first tablet, but it can take up to 3 days before the full effects are seen, if taken regularly twice a day.

Side Effects

Are there any side effects?

Like all medicines, Naproxen can cause side effects in some people. These can include confusion, changes in vision, ringing in the ears, dizziness, tiredness and headaches. 

If you experience any of these side effects, it’s important to speak to your GP or pharmacist, who can provide you with further advice. 

Naproxen can also cause indigestion, nausea and vomiting. If you experience this, you must stop taking the medicine and speak to your GP.

Is there anybody who should not use Naproxen?

Naproxen is not suitable for women who are pregnant, breastfeeding or trying to conceive. It is also not recommended for patients who have the following conditions:

  • Heart problems
  • Liver disease
  • Kidney disease
  • Asthma 
  • Heart failure
  • Heart attack
  • Stroke or mini stroke
  • Clotting disorders
  • Peripheral arterial disease
  • High blood pressure
  • Chronic obstructive pulmonary disease
  • Alcohol dependency
  • A history of stomach or duodenal ulcers
  • A history of gastro-intestinal bleeding 
  • A history of gastro-intestinal perforation
  • A history of gastro-intestinal cancer
  • A history of gastritis (or regular indigestion) 
  • Barretts oesophagus
  • Inflammatory bowel disease
  • Allergic disorders
  • Nasal polyps
  • Systemic lupus erythematosus (SLE)
  • Mixed connective tissue disorders

Patients who have a previous history of an allergic reaction to naproxen or another non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen, diclofenac or Volatarol (tablets, cream or gel) must not use this medication.

Information Leaflet

Patient Information Leaflet

Always read the patient information leaflet before starting treatment. View patient information leaflet.

Authored 02 April 2020 by Dr Clare Morrison, Reviewed 02 April 2020 by Liyya Patel, Siobhan Titre Last updated 02 April 2020

Recent Naproxen tablets Reviews

5 / 5

Based on 1 independent customer reviews taken by Feefo (see all Reviews).

"Great service"
By Penny (London) on 06 April 2023


Great price and very good value. Better price than branded items in high street pharmacy


A very thorough questionnaire to ensure the requested medication was safe and appropriate. Quick response followed authorising the meds and confirming order and delivery date.

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