Our goal is to help you find the option that’s right for your needs, and guide you through the change with expert support.
Clinical studies show people using Wegovy lose around 15% of their body weight on average over 68 weeks
We’ll match you to a suitable Wegovy dose equivalent to your current Mounjaro dose, so your treatment continues without interruption.
Wegovy is now significantly less expensive per pen. It’s also the first GLP-1 licensed for heart health benefits, is suitable for use with oral contraception, and tends to have fewer injection site reactions.
You don’t need to start over. Our clinicians can help find you a suitable Wegovy dose based on your current Mounjaro dose and tolerance.
Select your current Mounjaro dose to see the equivalent Wegovy dose.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
If you’ve experienced side effects, consider starting with a lower dose to help reduce the chance of new side effects when switching medications.
A prescriber will always check the dose is suitable for you before dispensing your order.
 Wegovy |  Mounjaro |
|---|---|
Lowest to highest dose price £99.99–£199.99 | Lowest to highest dose price £179.99–£309.99 |
Avg. weight loss* Up to 15% | Avg. weight loss* Up to 20% |
Active ingredient Semaglutide | Active ingredient Tirzepatide |
Schedule Weekly injection | Schedule Weekly injection |
Dose flexibility Increase, decrease or maintain monthly | Dose flexibility Increase, decrease or maintain monthly |
Suitable for oral contraception? Yes | Suitable for oral contraception? No |
Injection site reactions† 0.3% of patients | Injection site reactions† 8.6% of patients |
Licensed for heart health‡ Yes | Licensed for heart health‡ No |
* Effectiveness: In studies, the highest dose of Mounjaro (tirzepatide) plus healthy lifestyle changes led to an average weight loss of up to 20.9% in 36 weeks and 25.3% in 88 weeks. Wegovy (semaglutide) users lost around 15% of their weight in 68 weeks with diet and exercise changes.
† Injection site reactions: Long-term studies found these in 0.3% of Wegovy users and 8.6% of Mounjaro users.
‡ Heart health: Clinical trials show Wegovy can reduce the risk of heart attack, stroke and death from heart disease by up to 20% in people with obesity or who are overweight and have existing heart disease, even if they don’t have diabetes.
I had tried every diet under the sun. I finally plucked up the courage… and it has changed my life. I am happier, more confident, full of energy and able to run around after my children for longer. [It] has drastically improved my physical, emotional and mental health.
I was starting to get a pain in my knee which seems to have decreased a lot since losing the weight. I don't get any more back pain. It's made me a lot more confident within myself. I actually want to go out and do things. I want to go clothes shopping. I want to enjoy things with my kids.
I can do more. I feel more energetic. I can play more with my kids, whereas before I was restricted. It's mostly the breathlessness, the being slow, being out of breath, feeling heavy, not being able to put my clothes on properly because they were too tight. It's been a brilliant experience with MedExpress.
I used to hide away in oversized clothes, just trying to feel comfortable—but I had no confidence. Now, I'm fitting back into clothes I haven't worn in years, and I actually enjoy getting dressed in the morning. I feel happier, more confident, and like I'm finally showing up as myself.
It's making me more happy about myself. I'm feeling more confident. I'm not hiding. If my friend invites me for a coffee, I won't say no anymore. I'm dressing-up! I'm taking care of myself now. I feel more happy every day. I'm more talkative. I'm going to more family events.
MedExpress customers lose an average of 20.3% body weight in 12 months. That's four months faster than shown in studies (20.9% in 16 months).
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After 12 months
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Backed by our team of hundreds of in-house medical and clinical experts.
Medical Director
MBChB, MRCP, PhD
Catriona is a doctor with 20 years of clinical experience. She is committed...
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Senior GP and Medical Lead
BSc MB BS DCH MRCGP
Paul is an experienced GP with over 30 years working in the NHS and private...
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Consultant GP and Quality Lead
MBBS, BSc, MRCGP, DRCOG, PGDip Clinical De...
Safia is a GP with experience working in the NHS with a particular interest in...
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Superintendent Pharmacist
MPharm, MRPharmS, MPSI, PGDip
Declan is a pharmacist with 15 years of experience and is passionate about...
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Authored by Dr Clare Morrison. Last reviewed 01 February 2025 by Liyya Patel and Siobhan Titre.