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Answer a few questions
Complete a short online consultation. No waiting rooms or queues.
- With Wegovy, you can lose an average of 20.7% of your body weight in 72 weeks (1 year, 5 months)*
- Supports sustainable weight loss by reducing appetite and “food noise”
- Trusted by over 2.3 million people
*The evidence comes from STEP UP, a 72-week clinical trial in adults with a BMI of 27 or above using Wegovy (semaglutide 7.2mg). Studies in people with lower BMIs are limited, so results and safety are less certain. Weight loss cannot be guaranteed.
Results vary from person to person, but here's what the evidence shows:
- MedExpress customers using Mounjaro lose an average of 9% of their body weight in 3 months.*
- In clinical studies, Mounjaro users lost an average of 22.5% of their body weight** and Wegovy users lost an average of 20.7%*** after 72 weeks (around 1 year and 5 months).
*Based on average results from MedExpress patients prescribed Mounjaro. Individual results vary.
**SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.
***STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg). Individual results vary.
We offer two injectable treatments for weight management: Mounjaro and Wegovy. Both work in a similar way, but they contain different active ingredients.
Complete a free online consultation and we'll help you to understand your options, so you can choose the treatment that feels right for you.
Whatever you choose, our prescribers will review your consultation to make sure it's the right fit.
Many people with a BMI of 25 or above are eligible for weight loss medication. Eligibility also depends on your overall health. A clinician will review your medical history, any existing conditions, and your current medications to assess whether treatment is suitable for you.
How GLP-1s can support weight management
They work with your body's natural hunger signals to help manage appetite, blood sugar, and how full you feel.- Silence “food noise”They work on appetite signals in the brain, which can help reduce frequent thoughts about food and make it easier to eat less.
- Stay fuller after eatingThey slow how quickly food leaves your stomach, helping you feel satisfied for longer after meals.
- Help stabilise blood sugarThey support your body’s natural insulin response, which can help reduce blood sugar spikes and dips that may lead to cravings or energy crashes.
Trusted by over
1.4 million
weight loss customers
Trusted by over
1.4 million
weight loss customers
Results that speak for themselves
Before
6 months
I had tried every diet under the sun. I finally plucked up the courage… and it has changed my life. I am happier, more confident, full of energy and able to run around after my children for longer. [It] has drastically improved my physical, emotional and mental health.
Rosie G. lost 25kg after 6 months
Before
8 months
Within a week, I noticed a huge difference. After a month, when I started to see changes in my body, that's when all the benefits really kicked in. I honestly would say it's been life-changing—and I've told other people the same. It's not a wonder drug, but it is a life-changing process.
Paul H. lost 35kg after 8 months
Before
4 months
I can do more. I feel more energetic. I can play more with my kids, whereas before I was restricted. It's mostly the breathlessness, the being slow, being out of breath, feeling heavy, not being able to put my clothes on properly because they were too tight. It's been a brilliant experience with MedExpress.
Magdalena S. lost 22kg after 4 months
Before
4 months
[It] has changed my life. I am finally eating to fuel my body. Emotional binge eating is no longer a part of my life. MedExpress has been a fantastic company to deal with and I can't recommend them enough. Thank you for helping me get my life back!”
Kirsten D. lost 23kg after 4 months
Before
6 months
It's so easy and quick to take my injection [Treatment]. I've been overweight for my whole life — to be able to take that worry and stress away— you don't realise how much room it takes up. I've been able to sit down and create a schedule for myself, it's given me some space back.
Dorothy A. lost 15kg after 6 months
Before
4 months
I used to hide away in oversized clothes, just trying to feel comfortable—but I had no confidence. Now, I'm fitting back into clothes I haven't worn in years, and I actually enjoy getting dressed in the morning. I feel happier, more confident, and like I'm finally showing up as myself.
Natasha T. lost 29kg after 4 months
Before
6 months
The biggest thing it's taught me is about food noise. I didn't realise it was such an issue for me, but I really suffered badly with food noise. And the medication blocks it. I feel that it [Treatment] gives me that opportunity to pick better food, so my choices are better and healthier.
Leanne H. lost 25kg after 6 months
Before
3 months
I was starting to get a pain in my knee which seems to have decreased a lot since losing the weight. I don't get any more back pain. It's made me a lot more confident within myself. I actually want to go out and do things. I want to go clothes shopping. I want to enjoy things with my kids.
Roisin S. lost 19.5kg after 3 months
Before
4 months
It's making me more happy about myself. I'm feeling more confident. I'm not hiding. If my friend invites me for a coffee, I won't say no anymore. I'm dressing-up! I'm taking care of myself now. I feel more happy every day. I'm more talkative. I'm going to more family events.
Premila C. lost 23kg after 4 months
These customers received compensation for sharing their experience.
How much weight
could you lose?
In 72 weeks, people taking Mounjaro 15mg in a clinical study lost an average of 22.5% of their body weight when taken as directed. This means that someone who weighs 100kg may lose an average of 22.5kg in 72 weeks (1 year, 5 months). This is an example only. It is not a prediction of individual results.**SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.How it works
Step 2
Choose your treatment
Our qualified clinicians review your information and recommend treatment if it’s right for you.
Step 3
Get your treatment delivered
If prescribed, your treatment will arrive directly to you in discreet packaging.
Compare weight loss treatments
All options support meaningful weight loss and are backed by strong clinical evidence. The right choice for you depends on your goals, lifestyle and budget.
 Mounjaro Pen |  Wegovy Pen |  Wegovy Pill |  Orlistat |
|---|---|---|---|
First month from £179.99 | First month from £99.99 | First month from £100.00 | First month from £21.99 |
Needles? Yes | Needles? Yes | Needles? No | Needles? No |
Format Injection | Format Injection | Format Oral tablet | Format Oral capsule |
How often Once a week | How often Once a week | How often Once a day | How often 3 times a day |
Fasting required? NoNo food, drink or timing restrictions. | Fasting required? NoNo food, drink or timing restrictions. | Fasting required? YesEmpty stomach, with no more than 120ml water, 30min fast before food, drink or other medication. | Fasting required? NoTake one capsule with a drink at each main meal that contains fat, up to a max of 3 per day. |
Avg. weight loss 22.5% in 72 weeks1at the highest dose | Avg. weight loss 20.7% in 72 weeks2at the highest dose | Avg. weight loss 16.6% in 64 weeks3at the highest dose | Avg. weight loss 5% in 26 weeks4 |
Active ingredient Tirzepitide | Active ingredient Semaglutide | Active ingredient Semaglutide | Active ingredient Orlistat 60mg |
Storage Refrigerated | Storage Refrigerated | Storage Room temperature | Storage Room temperature |
Digestive side effects Very common(Inc. nausea, vomiting, diarrhoea, and constipation) | Digestive side effects Very common(Inc. nausea, vomiting, diarrhoea, and constipation) | Digestive side effects Very common(Inc. nausea, vomiting, diarrhoea, and constipation) | Digestive side effects Very common(Inc. wind, oily spotting, sudden or more frequent bowel motions and soft stools) |
Frequently asked questions
GLP-1 medications mimic a hormone your body naturally produces to help regulate appetite. They work by helping you feel fuller for longer, which can reduce how much you eat over time.
Many people with a BMI of 25 or above are eligible for weight loss medication. Eligibility also depends on your overall health. A clinician will review your medical history, any existing conditions, and your current medications to assess whether treatment is suitable for you.
GLP-1 medications are taken as a weekly injection using a pre-filled pen. You inject it yourself into your stomach, thigh, or upper arm. The pen is designed to be straightforward to use, and we'll explain exactly how before you start with guides and videos.
The most common side effects are nausea, diarrhoea, and constipation. These are usually mild and tend to ease as your body adjusts. Starting on a lower dose and increasing gradually helps reduce the likelihood of side effects, and we'll support you with it. If anything concerns you, get in touch and we'll help.
There's no fixed time limit. Treatment length depends on your progress and what your clinician recommends. Most people take GLP-1 medication alongside lifestyle changes like diet and exercise. If you stop, some weight regain is possible, which is why ongoing support is an important part of your treatment plan.
Start by completing your online consultation. Answer a few questions about your health, and a clinician will review your answers. If treatment is suitable for you, your medication will be prescribed and delivered to your home.
The consultation is completed online and takes around 2 to 5 minutes. You'll answer questions about your health history, current medications, and weight loss goals. You don't need to speak to anyone or attend any kind of appointment. A clinician reviews your answers and decides whether treatment is suitable for you.
No. The entire process is online, from consultation through to delivery. There are no in-person appointments required.
Yes. Your medication arrives in plain, unmarked packaging with nothing on the outside to indicate what's inside. There's no need to visit a pharmacy or collect anything in person.
The price covers your medication, delivery, and ongoing support from our team of experts. Everything is included, with no hidden fees.
GLP-1 medications are started at a lower dose and increased gradually as your body adjusts. Many people see meaningful results without reaching the highest dose, and you only move up when you and your clinician agree you're ready. The price reflects whichever dose you're taking, so you're always in control of both your treatment and your costs.
You pay when you complete your order. If a clinician decides treatment is not suitable for you, we'll automatically refund you in full.
No. There's no minimum term or lock-in contract. You can stop treatment at any time.
Some GLP-1 medications are available on the NHS, but access is currently very limited and typically requires a referral to a specialist weight management service, with significant waiting times. MedExpress offers a private alternative, meaning you can access treatment through an online consultation.
Once you start treatment, you'll have ongoing access to our clinical team. We'll also send you tailored guides and videos as your treatment progresses to help you get the most from it. You can get in touch at any time if you have questions, need advice, or want to review your treatment.
You can get in touch with our clinical team through our website. We aim to respond as quickly as possible. If you're experiencing a medical emergency, call 999.
Switching treatment is straightforward. You can explore your options on our website, or get in touch if you'd like some support finding the right fit.
Yes, and it's more common than you might think. If your current treatment isn't giving you the results you hoped for, or doesn't suit you, our clinical team can review your options and recommend an alternative if appropriate.
Let us know as soon as possible. Get in touch through our website and we'll make sure your treatment is still right for you.
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