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Medicated weight loss treatments

85,000+ service reviews
  • Lose an average of 22.5%* of your body weight with flexible options for Mounjaro, Wegovy, Alli and Orlistat
  • Find the right treatment for you with no GP referral required
  • Access ongoing support from our medical team of experts
Clinician

After answering some quick health questions, we'll recommend suitable treatments for you.

Dr Adam Abbs, Medical Director

*SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.

Trusted by over

1 million

weight loss customers

CQC logoGeneral Pharmaceutical Council logoLegitScript logo
CQC logoGeneral Pharmaceutical Council logoLegitScript logo
MedExpress is a UK-based regulated pharmacy

Clinically proven treatments for sustainable weight loss

Licensed options shown to support long-term results when combined with healthy lifestyle changes.

Mounjaro medication

Mounjaro®

Most effective dual action GLP-1

Lose an average of 22.5% of your body weight in 72 weeks (1 year, 5 months)*

Contains tirzepatide, which helps make you feel fuller, reduces cravings and supports metabolism

Easy to use weekly injection

Learn more
Check your eligibility
Wegovy medication

Wegovy®

Approved to cut heart disease risk**

Lose an average of 20.7% of your body weight in 72 weeks (1 year, 5 months)***

Contains semaglutide, which helps make you feel fuller and reduces cravings

Easy to use weekly injection

Learn more
Check your eligibility
Alli capsule

Alli®

Oral capsules

Lose an average of 5% body weight in 16 weeks†

Contains orlistat, which reduces how much fat your body absorbs from food

Take 3 times daily with meals

Learn more
Check your eligibility
Orlistat capsule

Orlistat

Oral capsules

Lose an average of 10% body weight in 2 years§

Reduces absorption of fat from food

Lose 50% more weight than dieting alone

Learn more
Check your eligibility

*SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.

**STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg). Individual results vary.

***SELECT study; Wegovy shown to cut the risk of major cardiovascular events by 20% in adults with obesity and heart disease. Individual results vary.

†16-week study of overweight adults using orlistat 60mg. Individual results vary.

§2-year study of adults with obesity using orlistat 120mg. Individual results vary.

Results that speak for themselves

Rosie before
Before
Rosie after
6 months
I had tried every diet under the sun. I finally plucked up the courage… and it has changed my life. I am happier, more confident, full of energy and able to run around after my children for longer. [It] has drastically improved my physical, emotional and mental health.

Rosie G. lost 25kg after 6 months

Paul before
Before
Paul after
8 months
Within a week, I noticed a huge difference. After a month, when I started to see changes in my body, that's when all the benefits really kicked in. I honestly would say it's been life-changing—and I've told other people the same. It's not a wonder drug, but it is a life-changing process.

Paul H. lost 35kg after 8 months

Magdalena before
Before
Magdalena after
4 months
I can do more. I feel more energetic. I can play more with my kids, whereas before I was restricted. It's mostly the breathlessness, the being slow, being out of breath, feeling heavy, not being able to put my clothes on properly because they were too tight. It's been a brilliant experience with MedExpress.

Magdalena S. lost 22kg after 4 months

Kirsten before
Before
Kirsten after
4 months
[It] has changed my life. I am finally eating to fuel my body. Emotional binge eating is no longer a part of my life. MedExpress has been a fantastic company to deal with and I can't recommend them enough. Thank you for helping me get my life back!”

Kirsten D. lost 23kg after 4 months

Dorothy before
Before
Dorothy after
6 months
It's so easy and quick to take my injection [Mounjaro]. I've been overweight for my whole life — to be able to take that worry and stress away— you don't realise how much room it takes up. I've been able to sit down and create a schedule for myself, it's given me some space back.

Dorothy A. lost 15kg after 6 months

Natasha before
Before
Natasha after
4 months
I used to hide away in oversized clothes, just trying to feel comfortable—but I had no confidence. Now, I'm fitting back into clothes I haven't worn in years, and I actually enjoy getting dressed in the morning. I feel happier, more confident, and like I'm finally showing up as myself.

Natasha T. lost 29kg after 4 months

Leanne before
Before
Leanne after
6 months
The biggest thing it's taught me is about food noise. I didn't realise it was such an issue for me, but I really suffered badly with food noise. And the medication blocks it. I feel that it [Mounjaro] gives me that opportunity to pick better food, so my choices are better and healthier.

Leanne H. lost 25kg after 6 months

Roisin before
Before
Roisin after
3 months
I was starting to get a pain in my knee which seems to have decreased a lot since losing the weight. I don't get any more back pain. It's made me a lot more confident within myself. I actually want to go out and do things. I want to go clothes shopping. I want to enjoy things with my kids.

Roisin S. lost 19.5kg after 3 months

Premila before
Before
Premila after
4 months
It's making me more happy about myself. I'm feeling more confident. I'm not hiding. If my friend invites me for a coffee, I won't say no anymore. I'm dressing-up! I'm taking care of myself now. I feel more happy every day. I'm more talkative. I'm going to more family events.

Premila C. lost 23kg after 4 months

These customers received compensation for sharing their experience.

Up to 9× more effective than diet and exercise alone*

Illustration of weight loss using GLP-1 injectable treatments showing it is 6 times more effective than diet alone
*SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.

How it works

Online consultation illustration
1

Answer quick questions

No GP or pharmacy visits, just a quick online consultation.

MedExpress medication illustration
2

Choose your treatment

Select from our recommended UK-licensed medications.

Discreet packaging illustration
3

Get it delivered fast

We’ll deliver direct to you, in discreet packaging.

See all treatments
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The thing I like most is the aftercare. I get really helpful emails with tips and advice. After week one I’m 6lb down, so let’s see where it takes me on my weight loss journey.

Sonia, weight loss customer
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Products are very effective. I’ve lost weight already in just 14 days so happy. Would recommend this company highly. In fact I’ve already introduced 3 people to MedExpress.

Shireen, weight loss customer
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I am one week into treatment and feeling good — less cravings and fuller for longer in between meals. The website is really informative and ordering a straightforward process.

Mrs Roe, weight loss customer

FAQs

MedExpress is a London-based online pharmacy backed by a team of experienced healthcare professionals. All our clinicians are based and registered in the UK. We prescribe prescription treatments through our quick online consultation, and they're shipped quickly and discreetly to your home.

Simply start a free online consultation. Our prescribers will recommend suitable medications for you to choose from and, once you're happy, they will issue a prescription. Your order will be delivered quickly and discreetly, directly to your home.

Yes, your medical data and order history is completely confidential. Only our pharmacy staff and prescribers can view it.

Yes, we only use plain, discreet packaging without any branding or labels.

Get started

Why use MedExpress?

  • No GP or pharmacy visit needed

  • No ongoing subscriptions

  • Delivered in logo-free packaging

  • Free sharps bin with your first order

Not sure? Start a free consultation to see our recommendation.

Authored by Dr Zoë Lees. Last reviewed 16 February 2026 by Liyya Patel.