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Malarone & Generic Malarone information
Side effects with Malarone are less common and severe than other anti-malaria drugs.
Side effects may include: rashes, abdominal pain, headaches, anorexia, nausea, diarrhoea, dizziness, change in sleep pattern, coughing and mouth ulcers.
It contains two medicines, atovaquone and proguanil hydrochloride, which both work in different ways to stop infection with the malaria parasite (Plasmodium falciparum). Malaria is spread by the bite of an infected mosquito, which passes the malaria parasite into the bloodstream. Malarone prevents malaria by killing this parasite. For people who are already infected with malaria, Malarone also kills these parasites.
Malaria is a serious tropical disease spread by mosquitoes. If malaria is not diagnosed and treated promptly, it can be fatal.
Malaria is not a problem in the UK. More information about the risk of malaria in specific countries can be found on the Fit for Travel website.
Find out if there is a malaria risk in the area you are visiting. To check whether you need to take preventative malaria treatment for the countries you are visiting, see the Fit for Travel or the National Travel Health Network and Centre (NaTHNaC) websites. Aspects of travel may increase the risk e.g. rural travel, rainy season or unscreened accommodation.
Use clothing to protect the skin, particularly between dusk and dawn when mosquitoes feed. Use DEET-based insect repellent on exposed areas of skin. Sleep under a mosquito net that is impregnated with insecticide. Use air conditioning (if available) and plug in vapourisers to protect your room.
The antimalarial tablets recommended for you will depend not only on effectiveness but also on suitability, side effects, cost and which regime suits you best. Tablets must be taken regularly according to the manufacturer’s instructions. Delayed illnesses - the incubation period of benign (mild) malaria may be long (up to a year or more).
If you experience any flu-like symptoms after returning you should seek immediate medical attention and tell the doctor about your background and recent travel history. (Particularly within 3 months of return but even up to 1 year and say you have been to a malarious area.)
You may need to take a supply of personal emergency treatment abroad with you if you are going to be remote from medical facilities since treatment should always be started promptly. Discuss this option with a Travel Advisor or other healthcare professional.
There may be alternative anti-malarial tablets that are suitable for your trip. Always check your destination(s) on http://www.fitfortravel.nhs.uk/ to determine which malaria tablets are suitable for your trip. For advice on your travel destinations visit Central Travel Clinic.
Always read the patient information leaflet before commencing treatment.
View patient information leaflet.One tablet daily with food or a milky drink at about the same time each day.
Start taking the tablets 1-2 days before you enter the malaria area and continue until one week after you leave.
Malarone tablets are not recommended for malaria prophylaxis in persons under 40 kg bodyweight.
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Dr Bryony Henderson
Dr. Bryony Henderson joins HeliosX as Medical Director for the UK and US, bringing extensive clinical operations, governance, and digital health experience from Kry/Livi and Numan. A recognised clinical voice, she has contributed to award-winning campaigns, published on health inequalities, and appeared across major national media. At HeliosX, she leads clinical governance and quality and supports the delivery of safe, innovative, scalable care.
Dr Adam Abbs
Adam is a doctor and advocate for increasing access to healthcare internationally. He has extensive experience in video consultations, technology-enabled examinations, remote biomarker testing, and education. He is a published author and has medical licenses in the UK, Spain and Republic of Ireland.
Dr Safia Hussain
Consultant GP and Quality Lead
MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology
Safia is a GP with experience working in the NHS with a particular interest in diabetes and weight loss management. She is passionate about the power of digital healthcare and oversees our approach to patient safety and regulatory compliance.
Declan Lismore
Declan is a pharmacist with 15 years of experience and is passionate about digital healthcare. He has extensive experience across all pharmacy sectors in the UK and Ireland. He has led the clinical and regulatory functions of some of the biggest pharmacy organisations in the UK and is excited about the future of the industry.