Step 1
Answer a few questions
Complete a short online consultation. No waiting rooms or queues.
UK registered pharmacy
UK licensed treatments
Trusted by over 1.5 million people
Epiduo Gel information
As with all medicines applied to the skin in the treatment of acne, you may not see results for up to eight weeks. It is important to be consistent in your application of this gel in order for it to work properly.
One study compared the efficacy of Epiduo to a placebo and showed that after 12 weeks of treatment, 27.5% of patients using Epiduo were clear or almost clear of acne compared to 9.9% of patients who used a placebo. The same study also compared Epiduo to each single active ingredient that is in it. After 12 weeks, adapalene had a success rate of 15.5% and benzoyl peroxide was 15.4%.
Epiduo is not suitable for those with a hypersensitivity to any of the ingredients. Do not use in pregnancy. Avoid sunlight and UV lamps while using this medicine. Do not use other acne products containing retinoids or benzoyl peroxide while using this medicine or products that are irritating, drying or exfoliating to the skin.
Some people can experience stinging sensation, dryness, scaling and burning sensitivity when they first use this medicine. This presents worst during the first week of use and then tends to settle.
Always read the patient information leaflet before commencing treatment.
View patient information leaflet.Epiduo is a gel that is used in the treatment of moderate to severe acne. It contains two active ingredients; benzoyl peroxide and adapalene. These ingredients are both used to treat acne and they work in different ways.
Benzoyl peroxide is an antimicrobial agent and works by killing bacteria on the skin.
Adapalene belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.
Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.
Do not apply to broken skin.
Epiduo is a prescription only medicine and cannot be bought over the counter. If you are interested in this medicine, why not fill out our consultation questionnaire? This will be reviewed by one of our expert prescribers who will advise if this medicine is suitable and safe for you.
85,000+ verified customer reviews
“Impressively quick service”
Impressively quick service. Easy site to navigate and meds delivered by reliable Royal Mail, so well pleased. Thank you!
“My full 5 star approval”
Great service, easy to navigate the questionnaire and far quicker service than waiting for the NHS services to approve and dispense your meds. Completely legitimate products, unlike so many other bogus sites. I have placed a couple of orders, even today, a Saturday, with estimated delivery this Monday. Awesome! This company has my full 5 star approval.
“Excellent service from the start”
Full information, quick delivery, follow up email. Professional would not purchase from anyone else.
“Very happy”
Fantastic service and very fast delivery, very happy with this service.
“Very fast delivery”
Very fast delivery, I am happy with the speed that I got to order what I needed and fast delivery, really needed to start taking the product. Thank you.
“Infinitely quicker”
Such an easy way to get medication quickly. Superb service and quick delivery. I couldn't even get through to my Drs so although this costs a bit more it's infinitely quicker.
“No hassle”
Fantastic and quick response, no hassle trying to get a doctor appointment, thanks MedExpress.
“I highly recommend them”
I have used them many times & the procedure is very easy & the delivery very quick.
“This is a brilliant service”
This is a brilliant service and so quick and efficient. I would have had to wait god knows how long for a GP appointment for this medication.
“Aftercare very good”
Checked properly by a doctor before medication was prescribed and aftercare very good. Received yesterday kept up to date with the delivery and had to sign for which I like so there's no missing parcel. Highly recommended.
“I would recommend!”
Trustworthy, professional and speedy delivery service. I have used this pharmacy a few times and I would recommend!
How it works
Step 2
Choose your treatment
Our qualified clinicians review your information and recommend treatment if it’s right for you.
Step 3
Get your treatment delivered
If prescribed, your treatment will arrive directly to you in discreet packaging.
Delivery options
Royal Mail 1st Class£2.90
Usually delivered the next working day
Special Delivery 1pm£5.95
Guaranteed next working day by 1pm
Special Delivery 9am£13.95
Guaranteed next working day by 9am
Post Office Collection£3.95
Usually collection next working day
Backed by our experienced UK-based medical team
Dr. Bryony Henderson
Dr. Bryony Henderson is Medical Director for MedExpress UK, bringing extensive experience in clinical operations, governance and digital health. She has previously held roles dedicated to delivering safe, scalable care across well-known brands. She is a recognised clinical voice contributing to award-winning campaigns, publishing on health inequalities, and appearing across national media. Here, Bryony leads clinical governance and quality, supporting the delivery of safe, innovative and accessible healthcare.
Adedayo Titiloye
Adedayo Titiloye is Superintendent Pharmacist responsible for the safe and compliant delivery of pharmacy services across MedExpress. He brings experience across community pharmacy and regional operations, including leadership roles within one of the UK’s largest independent pharmacy groups. Here, Ade focuses on building high-performing teams, improving processes and ensuring pharmacy services deliver safe, effective care at scale.
Dr. Carla Rodrigues
Dr. Carla Rodrigues is Head of Medical Operations at MedExpress, having previously held leadership roles in primary care networks and across well-known healthcare organisations, and has led scientific society groups in the field of sexual medicine. She has also completed training with MIT, Harvard and INSEAD. At HeliosX, Carla leads medical operations in the UK, overseeing the delivery of safe care pathways and upholding high standards in prescribing and clinical governance.
Dr. Kavir Matharu
Dr. Kavir Matharu is a GP Lead at MedExpress, with 10 years’ experience across a range of healthcare settings. She is a practising GP with a background in complex healthcare consulting, having worked on high-level strategic and operational challenges within the health system. She was also selected for a leadership fellowship with the National Medical Director at NHS England. Kavir has a strong interest in healthcare leadership and system improvement, with a focus on high-quality, sustainable care.
Dr. Daryl Perera
Dr. Daryl Perera is a GP Lead at MedExpress, with experience across NHS primary care, urgent care and private practice. He has extensive experience in digital healthcare and clinical leadership, and oversees clinical governance and patient safety across our digital health services. His work spans urgent care and preventative medicine, with particular interests in men’s health, obesity management, and sport and exercise medicine. Daryl has worked across a range of NHS and private healthcare organisations and previously held a GP Director role.
Dr. Sophie Dix
Head of Medical Affairs
BSc (Hons), MSc, PhD
Dr. Sophie Dix is Head of Medical Affairs at MedExpress and a behavioural neuroscientist with over 25 years’ experience across the pharmaceutical industry, charity sector and health technology. Her work has focused on understanding how to manage and treat conditions affecting both mind and body, bringing together scientific insight with real-world care. Sophie is passionate about evidence and ensuring people have access to the right treatment at the right time.
Dr. Zoe Lees
Medical Writer
BSc (Hons), MSc, PhD
Dr. Zoe Lees is a Medical Writer at MedExpress, specialising in clear, evidence-based health communications. She completed her postgraduate research at the University of Glasgow, focusing on metabolic complications of pregnancy and the role of adipose tissue function. Zoe brings a strong scientific foundation to her work and is committed to delivering content that is both accurate and accessible, grounded in robust research.
Dr. Adam Abbs
Dr. Adam Abbs is Medical Director, International at MedExpress responsible for expanding the company into new markets. He has extensive experience in asynchronous and video consultations, technology-enabled remote examinations and home biomarker testing, with a particular interest in educating both patients and doctors. Adam is a published author and is licensed to practice medicine in the UK and across the EU, and is registered in Canada.
Liyya Patel
Liyya Patel is Deputy Chief Pharmacist at MedExpress UK, with over 10 years’ experience supporting the organisation’s growth and development. She is responsible for ensuring pharmacy services are safe, compliant and meet all regulatory standards, playing a key role in maintaining high-quality clinical care. Liyya previously worked in high-volume community pharmacy settings in Central London and is a qualified pharmacist and independent prescriber.
Dr. Olivia de Rougemont
Dr. Olivia de Rougemont is a GP Lead at MedExpress with over 12 years’ experience across the NHS and private sectors. She has extensive experience in digital and in-person care, with a particular interest in women’s health, preventative medicine, and delivering patient-centred support that feels clear and accessible. Olivia also leads and mentors GPs, and brings a global perspective shaped by her experience working across different healthcare systems.