Epiduo Gel

Acne Treatment

£33.00 Includes free private prescription
Only £33.00 per pump

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Epiduo Gel

  • 1 x 45g - £33.00
  • 2 x 45g - £62.00

What is Epiduo?

What is Epiduo?

Epiduo is a gel that is used in the treatment of moderate to severe acne. It contains two active ingredients; benzoyl peroxide and adapalene. These ingredients are both used to treat acne and they work in different ways.

Benzoyl peroxide is an antimicrobial agent and works by killing bacteria on the skin.

Adapalene belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.

How do I apply Epiduo?

Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.

Do not apply to broken skin.

How do I buy Epiduo?

Epiduo is a prescription only medicine and cannot be bought over the counter. If you are interested in this medicine, why not fill out our consultation questionnaire? This will be reviewed by one of our expert prescribers who will advise if this medicine is suitable and safe for you.

How long does it take to see results?

As with all medicines applied to the skin in the treatment of acne, you may not see results for up to eight weeks. It is important to be consistent in your application of this gel in order for it to work properly.

How effective is Epiduo?

One study compared the efficacy of Epiduo to a placebo and showed that after 12 weeks of treatment, 27.5% of patients using Epiduo were clear or almost clear of acne compared to 9.9% of patients who used a placebo. The same study also compared Epiduo to each single active ingredient that is in it. After 12 weeks, adapalene had a success rate of 15.5% and benzoyl peroxide was 15.4%.

Is there anybody who cannot use Epiduo?

Epiduo is not suitable for those with a hypersensitivity to any of the ingredients. Do not use in pregnancy. Avoid sunlight and UV lamps while using this medicine. Do not use other acne products containing retinoids or benzoyl peroxide while using this medicine or products that are irritating, drying or exfoliating to the skin.

Side Effects

Side Effects

Some people can experience stinging sensation, dryness, scaling and burning sensitivity when they first use this medicine. This presents worst during the first week of use and then tends to settle.

Information Leaflet

Patient Information Leaflet

Always read the patient information leaflet before commencing treatment. View patient information leaflet.

Authored 02 April 2020 by Dr Clare Morrison, Reviewed 02 April 2020 by Liyya Patel, Siobhan Titre Last updated 02 April 2020

Recent Epiduo Reviews

4.9 / 5

Based on 9 independent customer reviews taken by Feefo (see all MedExpress Reviews).

"Speedy excellent service"
By Natalie on 03 September 2020


Excellent service and professional products


Fast efficient and great service

"Lovely products and quick delivery."
By Diana (Enfield) on 22 July 2020


epiduo really helped with my acne


Great service ??

By DANIELA MARIANA on 19 March 2018


Very good and a good result


Recomand cu incredere

"Excellent service"
By MedExpress Customer on 08 April 2021


Excellent service, quick delivery


Quick delivery, professional service

"Highly recommend"
By MedExpress Customer on 01 January 2021


The product was exactly what I wanted and I have no complaints about the product whatsoever


Easy to use and incredibly fast service with good access and an easy to use service.

Read More Epiduo Reviews

Discreet Service

Plain packaging

Option to collect from
your local Post Office™

local branches

How our service works

It’s quick, easy, and safe to order from MedExpress — your fully regulated, London, United Kingdom based online pharmacy.

Free online

Start a free 2 minutes online consultation with simple questions about your health.


Our UK medical team will then recommend a treatment and issue a free prescription.


Your treatment will be sent direct from our London pharmacy in discreet packaging.

Watch our video to find out more

Our qualified team

All our doctors and pharmacists are based in the UK and are registered with the General Medical Council and General Pharmaceutical Council.

Dr Clare Morrison

General Practitioner (Prescriber)
GMC: 3441561

Avnish Patel

GPhC: 2079950

Liyya Patel

Superintendent Pharmacist
GPhC: 2083287

Choosing Generic vs Branded Epiduo


Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product before they can be sold - i.e. they offer the same quality, strength, stability and effectiveness.