UK registered pharmacy
UK licensed treatments
Trusted by over 1.5 million people
As with all medicines applied to the skin in the treatment of acne, you may not see results for up to eight weeks. It is important to be consistent in your application of this gel in order for it to work properly.
One study compared the efficacy of Epiduo to a placebo and showed that after 12 weeks of treatment, 27.5% of patients using Epiduo were clear or almost clear of acne compared to 9.9% of patients who used a placebo. The same study also compared Epiduo to each single active ingredient that is in it. After 12 weeks, adapalene had a success rate of 15.5% and benzoyl peroxide was 15.4%.
Epiduo is not suitable for those with a hypersensitivity to any of the ingredients. Do not use in pregnancy. Avoid sunlight and UV lamps while using this medicine. Do not use other acne products containing retinoids or benzoyl peroxide while using this medicine or products that are irritating, drying or exfoliating to the skin.
Some people can experience stinging sensation, dryness, scaling and burning sensitivity when they first use this medicine. This presents worst during the first week of use and then tends to settle.
Always read the patient information leaflet before commencing treatment.
View patient information leaflet.Epiduo is a gel that is used in the treatment of moderate to severe acne. It contains two active ingredients; benzoyl peroxide and adapalene. These ingredients are both used to treat acne and they work in different ways.
Benzoyl peroxide is an antimicrobial agent and works by killing bacteria on the skin.
Adapalene belongs to a group of medicines called retinoids (which includes tretinoin) and helps to reduce inflammation and black and white head formation on the outer layer of the skin. Adapalene is an advanced third generation retinoid which exhibits many of the same effects as previous generation medicines like tretinoin but is often tolerated better.
Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.
Do not apply to broken skin.
Epiduo is a prescription only medicine and cannot be bought over the counter. If you are interested in this medicine, why not fill out our consultation questionnaire? This will be reviewed by one of our expert prescribers who will advise if this medicine is suitable and safe for you.
Impressively quick service. Easy site to navigate and meds delivered by reliable Royal Mail, so well pleased. Thank you!
Great service, easy to navigate the questionnaire and far quicker service than waiting for the NHS services to approve and dispens...
Full information, quick delivery, follow up email. Professional would not purchase from anyone else.
Fantastic service and very fast delivery, very happy with this service.
Great prices and service. Delivered on time, every time. 10/10.
Very fast delivery, I am happy with the speed that I got to order what I needed and fast delivery, really needed to start taking t...
Such an easy way to get medication quickly. Superb service and quick delivery. I couldn’t even get through to my Drs so although t...
Extremely professional, competitively priced, quick delivery
Fantastic and quick response, no hassle trying to get a doctor appointment, thanks MedExpress.
I have used them many times & the procedure is very easy & the delivery very quick.
This is a brilliant service and so quick and efficient. I would have had to wait god knows how long for a GP appointment for this ...
Checked properly by a doctor before medication was prescribed and aftercare very good. Received yesterday kept up to date with the...
Very quick to dispatch and customer service excellent
Trustworthy, professional and speedy delivery service. I have used this pharmacy a few times and I would recommend!
Good prices, communication and speed of delivery.

No GP or pharmacy visits, just a quick online consultation.
No GP or pharmacy visits, just a quick online consultation. Share your symptoms and a brief medical history in around two minutes, all from the comfort of your home.

Select from our recommended UK-licensed medications.
Select from our recommended UK-licensed medications. You don’t need an existing prescription.

We’ll deliver direct to you.
We’ll deliver direct to you. We always use discreet logo-free packaging, so only you know what’s inside. After it arrives, get ongoing support from our team.
Usually delivered the next working day
Guaranteed next working day by 1pm
Guaranteed next working day by 9am
Usually collection next working day