If you’re thinking about starting a weight loss journey with Wegovy, you’re probably wondering what you can expect in the first month of treatment. Below, our experts give an overview of Wegovy and explain how your body adjusts to treatment in your first month. 

Understanding Wegovy

Wegovy is a popular glucagon-like peptide-1 (GLP-1) weight management medication. It is a weekly injectable medication that contains the active ingredient, semaglutide (the same ingredient in Ozempic). [1]

It works by mimicking the natural GLP-1 hormone that is released in your gut after eating and promotes weight loss in a few different ways:

• Slows digestion (gastric emptying) to help you stay satisfied between meals. [1]
• Keeps blood sugar steady by increasing insulin secretion after eating to reduce hunger. [1]
• Targets the part of your brain that controls appetite to decrease hunger levels. [1]
• Acts on the reward system in the brain to reduce cravings and ‘food noise’.

Week-by-Week Breakdown: What to Expect

Every Wegovy journey is different, but there are a few common experiences that you can expect in your first month.

Initial Adjustments and Finding a Routine

In the first few weeks, your body is adjusting to the medication and your new appetite. To make this adjustment period easier, we recommend establishing consistent habits early. Here are a few things you can do:

• Choose an injection day that works best for your routine and set a reminder on your phone or calendar so you never miss a dose.
• Start tracking changes in your body weight and waist circumference on a weekly basis so you can look back on your progress later.
• Celebrate non-scale victories as much as the numbers, because they signal lasting change. Examples include reaching your step count or noting increased energy levels.
• Set realistic milestones and reward yourself as you achieve them

Managing Common Side Effects

Nausea, vomiting, diarrhoea and fatigue are some of the most common side effects to experience as your body adjusts to your medication. [2]

Below we’ve included a few strategies to help make managing side effects easier:

• Try tracking your symptoms in a diary to help you figure out if certain foods make side effects worse.
• Try eating smaller meals more frequently so you don’t feel uncomfortably full.
• Make sure you’re getting enough sleep (we recommend 7-9 hours of sleep each night).
• Avoid foods that are spicy or high in fat as they can irritate your stomach.

For more tips on how to manage side effects, head to the MedExpress GLP-1 Weight Loss Guide.

Expected Weight Loss Timeline 

Everyone loses weight at different speeds, so it’s important to give Wegovy time to work, which is why our team recommends staying on treatment for at least six months. Whether you lose weight quickly at first or don’t see results until later, it’s important to remember that some people don’t see results until later. 

Case Study: Chloe’s First Month Results 

Even though Wegovy has been proven to work in studies, it’s also helpful to hear firsthand experience from real patients. Here’s what MedExpress customer Chloe has to say about her experience using weight loss treatment.

Before starting Wegovy, Chloe had tried everything to lose weight.

“I’ve been trying to lose weight for 14 years. As soon as I knew about this medication from my research, I ordered it the same night I found out it was available,” she says. 

Once she started Wegovy, she was pleased to see an impact on her appetite, something that no other weight loss method had been able to do as well. Chloe says:

“Management of my appetite was the biggest challenge, so the medication has really just been game-changing.” 

The good news is that the benefits extend well beyond the first month of treatment. When it comes to her Wegovy journey, Chloe says:

“It’s been nothing but positive – a miracle.”

Maintaining Momentum After Your First Month

After your first month, it’s important to keep building on the healthy habits you’ve started. This means staying consistent with your medication routine, eating a balanced diet and increasing your physical activity. Plus, at MedExpress, our clinical team is here to support you through your entire journey.

Ready to Start Your Weight Loss Journey?

If you’re ready to start your weight loss journey, the team at MedExpress can assess your eligibility and help you find a treatment that suits your lifestyle.

References:

1. Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen – Summary of Product Characteristics (SmPC) – (emc) [Internet]. www.medicines.org.uk. Available from: https://www.medicines.org.uk/emc/product/13799/smpc#gref
2. Wharton S, Calanna S, Davies M, Dicker D, Goldman B, Lingvay I, et al. Gastrointestinal tolerability of once‐weekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss. Diabetes, Obesity and Metabolism. 2021 Oct 4;24(1).