Medicated weight loss treatments

85,000+ service reviews
  • Lose an average of 20.7% of body weight in 72 weeks (1 year, 5 months)*
  • Weekly self-administered doses
  • Supports healthy weight loss by reducing appetite and making you feel fuller
Clinician

After answering some quick health questions, we'll recommend suitable treatments for you.

Dr Adam Abbs, Medical Director

*STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg). Individual results vary.

Available treatments

Start a consultation to learn more about the best option for you

Option 1
Option 2
Weight loss
An average of 22.5%*An average of 20.7%**
Works by
Reducing appetiteReducing appetite
Dose
Once a weekOnce a week
Each pack lasts
4 weeks4 weeks
Price from
£0.00£0.00

*SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.

**STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg). Individual results vary.

CQC logoGeneral Pharmaceutical Council logoLegitScript logo
CQC logoGeneral Pharmaceutical Council logoLegitScript logo
MedExpress is a UK-based regulated pharmacy

Up to 9× more effective than diet and exercise alone*

Illustration of weight loss using GLP-1 injectable treatments showing it is 6 times more effective than diet alone

*SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.

Trustpilot logo

The thing I like most is the aftercare. I get really helpful emails with tips and advice. After week one I’m 6lb down, so let’s see where it takes me on my weight loss journey.

Sonia, GLP-1 customer
Trustpilot logo

Products are very effective. I’ve lost weight already in just 14 days so happy. Would recommend this company highly. In fact I’ve already introduced 3 people to MedExpress.

Shireen, GLP-1 customer
Trustpilot logo

Amazing experience. Excellent packaging, highest standards. Sharps bin, swabs and needles included. Trustworthy and professional. Thanks team 💓

Sally, GLP-1 customer

How it works

  1. Step 1 illustration

    1. Answer quick questions

    No GP or pharmacy visits, just a quick online consultation.

  2. Step 2 illustration

    2. Choose a treatment

    Select from our recommended UK-licensed weight loss treatments.

  3. Step 3 illustration

    3. Get it delivered direct

    Your treatment arrives in discreet packaging, direct to your door.

FAQs

Injectable GLP-1 treatments are medicines that come in a pre-filled pen that are self-administered at home once a week.

GLP-1 treatments mimic a natural hormone in your gut. It regulates your blood sugar levels and keeps you feeling full for longer, and can help you lose nearly 2x more than other popular medications.

The pens are simple to use and the needles are very small, so it's relatively pain-free and easy to get used to.

Injectable GLP-1 treatments are one of the most effective types of weight loss medicines available.

In 72 weeks, people taking Wegovy 7.2mg in a clinical study lost an average of 20.7% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 20.7kg on average in 72 weeks (1 year, 5 months).*

In 72 weeks, people taking Mounjaro 15mg in a clinical study lost an average of 22.5% of their body weight when taken as directed. This means that someone who weighs 100kg may lose 22.5kg on average in 72 weeks (1 year, 5 months).**

These are examples only. It is not a prediction of inBodyidual results.

Everyone responds differently, and progress depends on your dose, lifestyle, and how your body adapts over time. Our medical team will help you find what works best for you.

*SURMOUNT-1, 72-week study of adults with obesity using Mounjaro (tirzepatide 15mg). Individual results vary.

**STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 7.2mg). Individual results vary.

Injectable weight loss treatments are suitable for people with a BMI over 30. For inBodyiduals with weight related health concerns, they may be eligible with a BMI over 27. These related concerns include high blood pressure, diabetes, heart disease and raised cholesterol.

If you have Type 2 diabetes and a BMI less than 27, we can't prescribe you injectable GLP-1 treatments for weight loss.

If our clinicians review your consultation and photo, and injectable treatment is not the right option for you, we will immediately provide you with a full refund.
To get started, complete our quick online consultation. This allows us to recommend the best injectable treatment for you.
We’ll also request your BMI, a full-length photo, and your GP’s details before completing your prescription. This is to ensure we can offer you effective, and safe, weight loss treatment.

Injectable weight loss medication comes in a pre-filled pen. It needs to be used once weekly, on the same day. The pen itself is simple to use and the needles are very small, so it's relatively pain-free and easy to get used to.

Treatments can be injected in the abdomen, thigh or upper arm at any time during the day, with or without food. It's recommended that you use it around the same time each week — this will regulate the medication's effectiveness.

You'll receive clear instructions with your first order on the specifics for applying your treatment confidently. Our team are also on hand to answer any questions.

Your treatment starts at a low dose and then increases every four weeks. When you first start treatment, you'll be prescribed the starting dose to use once a week, for four weeks. The dose will then be increased after every four weeks until you reach the recommended maintenance dose.

The clinical team will review your weight with every order to ensure this product is working for you. This way we can ensure the dose which you peak at is optimal for you.

When you order an injectable treatment for the first time, we'll provide you with a pen and accessories for your 4 doses for your first 28 days of treatment. It's important to store it in a refrigerator between 2–8°C. Injectable treatments come in a single-dose pen that requires no mixing. You will also receive:
  • A sharps bin with your first order
  • Swabs to clean the skin area prior to injecting
  • An instruction leaflet
  • Extra tips that can help you lose weight
To get started, complete a consultation for an injectable weight loss pen and select the lowest dose. With each subsequent order, you will receive the next pen at the required strength.

Like all medicines, injectable GLP-1 treatments can cause side effects, including nausea, vomiting, constipation and diarrhoea. Not everybody experiences them, but if you do, they usually settle after a few weeks once you get used to the medication. One of the reasons for the gradual increase in medication every four weeks is to give your body the chance to tolerate the medication so that these side effects are less likely to happen or be less problematic.

If you develop abdominal pain, severe stomach problems or severe dehydration whilst taking this medication, you should seek medical advice immediately and advise that you are using this medication.

If you develop signs of an allergic reaction, such as difficulty in breathing, rash, swelling of the face, lips or tongue, then you should also seek help immediately.

Always read the patient information leaflet that's supplied with your treatment for full information regarding side effects.

Why use MedExpress?

  • No GP or pharmacy visit needed

  • No ongoing subscriptions

  • Delivered in logo-free packaging

  • Free sharps bin with your first order

Backed by our experienced UK-based medical team

Dr Adam Abbs picture

Dr Adam Abbs

Medical Director | MBBS, PGCCE, fHEA

GMC: 7078829

Dr Safia Hussain picture

Dr Safia Hussain

GP Lead | MBBS, BSc, MRCGP, DRCOG, PGDip Clinical Dermatology

Authored by Dr Zoë Lees. Last reviewed 16 February 2026 by Liyya Patel.