Choosing Generic vs Branded Circadin


Generic medicines contain the same active ingredient and are equally effective and equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product before they can be sold - i.e. they offer the same quality, strength, stability and effectiveness.


Jet Lag Treatment

£26.99 (includes free private prescription)
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  • 10 tablets - £26.99
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What is Circadin?

What is Circadin?

Circadin contains melatonin. Melatonin is a natural hormone that our body releases after the onset of darkness. It makes people feel sleepy and it helps to regulate the body’s circadian rhythm. Circadin is licensed to be used on its own for short-term use in people aged 55 and over, who find it difficult to get to, or to stay, asleep. It should not be used in people who cannot sleep due to a medical, mental or environmental cause. It is also used off-licence in the treatment of jet-lag. It has been found to be particularly effective in those who are travelling eastwards.

How can I buy Circadin?

Circadin is a Prescription Only Medicine (POM) and cannot be bought over the counter. If you are interested in this medicine, why not fill out our consultation questionnaire? This will be reviewed by one of our expert doctors who will advise if this medicine is suitable and safe for you.

Is there anybody who cannot use Circadin?

Circadin should not be taken by anybody with a hypersensitivity to any of the ingredients.

Circadin is not recommended for use in those with an autoimmune disease.

Circadin should be used in caution in people with renal or liver impairment and you should speak to your doctor before use as its use is not recommended.

Circadin interacts with various medicines and you should discuss with your doctor before use if you are taking other medications.

Some of the medicines that can interact with Circadin include; fluvoxamine, cimetidine, contraceptive or hormone replacement therapy oestrogens, quinolones, carbamazepine, and rifampicin.

Cigarette smoking while using Circadin can decrease Circadin levels and should be avoided while taking this medicine.

How do I take Circadin?

The usual dose is one 2mg tablet to be taken by mouth after food, 1 to 2 hours before bedtime. Tablets should be swallowed whole with a glass of water. Do not chew or crush.

Circadin can be used for up to 13 weeks.

Side Effects

Side Effects

By its nature, Circadin can cause drowsiness and so when using this medication no activities should be performed which would be dangerous to undertake when drowsy.

Some uncommon side effects include migraine, headache, dizziness, high blood pressure, abdominal pain, dry mouth, irritated skin, abnormal liver function tests, increased weight, nightmares, and anxiety.

Information Leaflet

Patient Information Leaflet

Always read the patient information leaflet before commencing treatment. View patient information leaflet.

Authored 02 April 2020 by Dr Clare Morrison, Reviewed 02 April 2020 by Liyya Patel, Siobhan Titre Last updated 02 April 2020

Recent Circadin Reviews

5 / 5

Based on 2 independent customer reviews taken by Feefo (see all MedExpress Reviews).

"Great service"
By Richard on 25 June 2018


It is great fir helping catch up with sleep and travel


Fast efficient delivery ,sent product requested , very happy with service

By MedExpress Customer on 05 November 2019


Very useful to keep sleep patterns regulated, especially when traveling.


Professional and fast service.

Read More Circadin Reviews

Discreet Service

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local branches

How our service works

It’s quick, easy, and safe to order from MedExpress — your fully regulated, London, United Kingdom based online pharmacy.

Free online

Start a free 2 minutes online consultation with simple questions about your health.


Our UK medical team will then recommend a treatment and issue a free prescription.


Your treatment will be sent direct from our London pharmacy in discreet packaging.

Watch our video to find out more

Our qualified team

All our doctors and pharmacists are based in the UK and are registered with the General Medical Council and General Pharmaceutical Council.

Dr Clare Morrison

General Practitioner (Prescriber)
GMC: 3441561

Dr Heather Currie

General Practitioner (Prescriber)
GMC: 2613354

Dr Syed Arfeen

Primary Care Physician
GMC: 6031426